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HSPB11
heat shock protein family B (small), member 11
Component of the IFT complex B required for sonic hedgehog/SHH signaling. May mediate transport of SHH components: required for the export of SMO and PTCH1 receptors out of the cilium and the accumulation of GLI2 at the ciliary tip in response to activation of the SHH pathway, suggesting it is involved in the dynamic transport of SHH signaling molecules within the cilium. Not required for ciliary assembly.
| Gene Name: | heat shock protein family B (small), member 11 |
| Synonyms: | HSPB11, C1orf41, HSPCO34, IFT25, Heat shock protein beta-11, Placental protein 25, PP25 |
| Target Sequences: | NM_016126 NP_057210.2 Q9Y547 |
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