HSPA8 / HSC70

heat shock 70kDa protein 8

Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP.

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Products

Proteins (18)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (12)

Target

HSPA8 / HSC70 (18)

Publications

No (18)

Tag

6His, N-terminus (2)

GST (2)

His (8)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Bovine (1)

Chicken (1)

Human (12)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (8)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (6)

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Human HSPA8 / HSC70 Protein (Recombinant His, N-Terminal) (Ser2-Asp646) - LS-G136135

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

71 kDa

Price:

10 µg/$289

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Human HSPA8 / HSC70 Protein (Recombinant His) - LS-G642

Source:

E. coli

Tag:

His

Price:

100 µg/$511; 500 µg/$1,348; 20 µg/$311

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Human HSPA8 / HSC70 Protein (Recombinant His) (aa534-615) - LS-G15147

Source:

E. coli

Tag:

His

Molecular Weight:

10.8 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HSPA8 / HSC70 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71056

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.7 kDa

Price:

20 µg/$1,107

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Mouse HSPA8 / HSC70 Protein (Recombinant His) (aa534-615) - LS-G15148

Source:

E. coli

Tag:

His

Molecular Weight:

10.7 kDa

Price:

10 µg/$275; 50 µg/$407; 100 µg/$652; 200 µg/$812; 1 mg/$1,893; 500 µg/$1,444; 5 mg/$2,843; 2 mg/$2,077

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Bovine HSPA8 / HSC70 Protein (Recombinant His) (aa534-615) - LS-G15150

Source:

E. coli

Tag:

His

Molecular Weight:

10.8 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Chicken HSPA8 / HSC70 Protein (Recombinant His) (aa534-615) - LS-G15152

Source:

E. coli

Tag:

His

Molecular Weight:

11.0 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat HSPA8 / HSC70 Protein (Recombinant His) (aa534-615) - LS-G15154

Source:

E. coli

Tag:

His

Molecular Weight:

11.0 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human HSPA8 / HSC70 Protein (Over-Expression Lysate 6His, N-terminus) (Ser2-Asp646) - LS-G26781

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

71 kDa

Price:

100 µg/$298

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Human HSPA8 / HSC70 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ser2-Asp646) - LS-G26921

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

71 kDa

Price:

200 µl/$283

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Human HSPA8 / HSC70 Protein (Recombinant GST) (Full Length) - LS-G28940

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

96.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HSPA8 / HSC70 Protein (Recombinant GST) (Full Length) - LS-G28937

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

96.8 kDa

Price:

10 µg/$479; 25 µg/$670

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HSPA8 / HSC70 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100862

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.7 kDa

Price:

100 µg/$494

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Human HSPA8 / HSC70 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88646

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.3 kDa

Price:

20 µg/$215

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Human HSPA8 / HSC70 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88647

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.7 kDa

Price:

20 µg/$150

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HSPA8 / HSC70 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105863

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.3 kDa

Price:

100 µg/$710

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Human HSPA8 / HSC70 Protein (Recombinant His) (Met1-Asp646) - LS-G97549

Source:

E. coli

Tag:

His

Molecular Weight:

72.4 kDa

Price:

100 µg/$721

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Human HSPA8 / HSC70 Protein (Recombinant His) - LS-G141258

Source:

E. coli

Tag:

His

Price:

50 µg/$348; 100 µg/$407

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