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HSPA5 / GRP78 / BiP
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
| Gene Name: | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| Synonyms: | HSPA5, BIP, Heat shock 70 kDa protein 5, MIF2, GRP-78, GRP78 |
| Target Sequences: | M19645 AAA52614.1 P11021 |
Publications (10)
1
NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet. Pepping JK, Freeman LR, Gupta S, Keller JN, Bruce-Keller AJ. American journal of physiology. Endocrinology and metabolism. 2013 304:E392-404. (WB; Mouse)
[PubMed:23233541]
[PMC:PMC3566505]
2
Cell-extrinsic effects of tumor ER stress imprint myeloid dendritic cells and impair CD8 T cell priming. Mahadevan NR, Anufreichik V, Rodvold JJ, Chiu KT, Sepulveda H, Zanetti M. PloS one. 2012 7:e51845.
[PubMed:23272178]
[PMC:PMC3525659]
Related Antibodies: LS-C165064.
3
Proteomic analysis of solid pseudopapillary tumor of the pancreas reveals dysfunction of the endoplasmic reticulum protein processing pathway. Zhu Y, Xu H, Chen H, Xie J, Shi M, Shen B, Deng X, Liu C, Zhan X, Peng C. Molecular & cellular proteomics : MCP. 2014 13:2593-603. (WB; Human, Rat)
[Full Text Article]
[PubMed:24997997]
[PMC:PMC4188989]
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Products
ELISA Kits
(20)
Type
Competitive EIA
(2)
Custom
(2)
Development Kit
(2)
Sandwich
(13)
Sandwich CLIA
(1)
Target
HSPA5 / GRP78 / BiP
(20)
Reactivity
Human
(5)
Mouse
(7)
Rat
(5)
Chicken
(1)
Pig
(1)
Product Group
DevKit DuoPlus
(2)
Format
12 x 8-Well Microstrips
(1)
96-Well Strip Plate
(16)
Antibody Pair and Standard
(2)
Publications
No
(19)
Yes
(1)
Sample Type
Cell Culture Supernatants
(6)
Cell Lysates
(6)
Plasma
(15)
Serum
(15)
Tissue Homogenates
(10)
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
12 x 8-Well Microstrips
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Competitive EIA
96-Well Strip Plate
Mouse
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Sandwich
96-Well Strip Plate
Mouse
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Sandwich CLIA
Mouse
0.156 - 10 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$871
Development Kit
Antibody Pair and Standard
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,302; 1000 Wells/$1,947
Development Kit
Antibody Pair and Standard
Rat
1.562 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,356; 1000 Wells/$2,037
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$783
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Competitive EIA
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Sandwich
96-Well Strip Plate
Mouse
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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