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HSP70 / Heat Shock Protein 70

The 70 kilodalton heat shock proteins (Hsp70s) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. Members of the Hsp70 family are strongly upregulated by heat stress and toxic chemicals, particularly heavy metals such as arsenic, cadmium, copper, mercury, etc. Hsp70 was originally discovered by FM Ritossa in the 1960s when a lab worker accidentally boosted the incubation temperature of Drosophila (fruit flies). When examining the chromosomes, Ritossa found a "puffing pattern" that indicated the elevated gene transcription of an unknown protein. This was later described as the "Heat Shock Response" and the proteins were termed the "Heat Shock Proteins" (Hsps). Hsp70 is also know as Hsp72.

HSP70 / Heat Shock Protein 70 Target Details

Target Name: HSP70 / Heat Shock Protein 70
Target Abbreviation: HSP70

Publications (4)

1
Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis. Zhang C, Wang Y, Zhou Z, Zhang J, Tian Z. Cancer immunology, immunotherapy : CII. 2009 58:1275-85. (WB) [PubMed:19139882]
2
Presence of diabetes autoantigens in extracellular vesicles derived from human islets. Hasilo CP, Negi S, Allaeys I, Cloutier N, Rutman AK, Gasparrini M, Bonneil É, Thibault P, Boilard É, Paraskevas S. Scientific reports. 2017 7:5000. (ICC, WB, Flo; Human, Hamster) [Full Text Article] [PubMed:28694505] [PMC:PMC5504025] Related Antibodies: LS-C231813.
3
Selenium Nanoparticles Pre-Treatment Reverse Behavioral, Oxidative Damage, Neuronal Loss and Neurochemical Alterations in Pentylenetetrazole-Induced Epileptic Seizures in Mice. Xiaona Yuan, Zhenshuai Fu, Pengfei Ji, Lubo Guo, Ali O Al-Ghamdy, Ali Alkandiri, Ola A Habotta, Ahmed E Abdel Moneim, Rami B Kassab. International journal of nanomedicine. 2020 September;15:6339-6353. [Full Text Article] [PubMed:32922005] [PMC:PMC7455605]
4
CXCR4 regulates Plasmodium development in mouse and human hepatocytes. Hironori Bando, Ariel Pradipta, Shiroh Iwanaga, Toru Okamoto, Daisuke Okuzaki, Shun Tanaka, Joel Vega-Rodríguez, Youngae Lee, Ji Su Ma, Naoya Sakaguchi, Akira Soga, Shinya Fukumoto, Miwa Sasai, Yoshiharu Matsuura, Masao Yuda, Marcelo Jacobs-Lorena, Masahiro Yamamoto. The Journal of experimental medicine. 2019 Aug;216:1733-1748. [Full Text Article] [PubMed:31189656] [PMC:PMC6683982] Related Antibodies: LS-C109068.
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Antibodies (193)
ELISA Kits (21)
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Primary (193)
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HSP70 / Heat Shock Protein 70 (218)
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HSP70 / Heat Shock Protein 70 Antibody - Anti-HSPA1A / HSP72 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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HSP70 / Heat Shock Protein 70 Rabbit Polyclonal Antibody
Coral, Fish, Atlantic hagfish, Beluga, Hamster, Pig, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Human, Monkey
ELISA, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
HSP70 / Heat Shock Protein 70 Antibody - PfHsp70, Malarial parasite lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Rabbit anti-Plasmodium falciparum Polyclonal (aa365-681) Antibody
Plasmodium falciparum
IF, WB
Unconjugated
25 µg/$327; 100 µg/$442
HSP70 / Heat Shock Protein 70 Antibody - PfHsp70, Malarial parasite lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Rabbit anti-Plasmodium falciparum Polyclonal (aa365-681) (FITC) Antibody
Plasmodium falciparum
IF, WB
FITC Conjugated
100 µg/$472
HSP70 / Heat Shock Protein 70 Antibody - PfHsp70, Malarial parasite lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Rabbit anti-Plasmodium falciparum Polyclonal (aa365-681) (Atto 594) Antibody
Plasmodium falciparum
IF, WB
Atto 594 Conjugated
100 µg/$479
HSP70 / Heat Shock Protein 70 Antibody - Formalin-fixed, paraffin-embedded human breast carcinoma stained with Heat Shock Protein 70 antibody.
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HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (W27) Antibody
Human
IHC
Unconjugated
0.1 ml/$284; 0.5 ml/$500; 1 ml/$737
HSP70 / Heat Shock Protein 70 Antibody - Anti-HSP70 / Heat Shock Protein 70 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (3A3) Antibody
Amphibian, Chicken, Fish, Drosophila, Mouse, Rat, Human, Yeast
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
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HSP70 / Heat Shock Protein 70 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$688
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HSP70 / Heat Shock Protein 70 Rabbit anti-Plasmodium falciparum Polyclonal (aa365-681) Antibody
Plasmodium falciparum
IF, WB
Unconjugated
25 µg/$500; 100 µg/$695
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
39.06 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
HSP70 / Heat Shock Protein 70 Antibody - Anti-HSP70 / Heat Shock Protein 70 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Mouse Monoclonal (N27F3-4) Antibody
Xenopus, Chicken, Fish, Drosophila, Pig, Hamster, Rat, Beluga, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Plant, Human, Monkey, C. elegans
IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
HSP70 / Heat Shock Protein 70 Antibody - Anti-HSP70 / Heat Shock Protein 70 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (5A5) Antibody
Amphibian, Chicken, Fish, Drosophila, Mouse, Rat, Human, Yeast
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
HSP70 / Heat Shock Protein 70 Antibody - Anti-HSP70 / Heat Shock Protein 70 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
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HSP70 / Heat Shock Protein 70 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HSP70 / Heat Shock Protein 70 Antibody - Hsp70 (C92) Mouse colon cancer.
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (C92F3A-5) Antibody
Chicken, Carp, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, C. elegans
ELISA, Flo, ICC, IHC, WB
Unconjugated
50 µg/$328; 200 µg/$460
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (Biotin) (C92F3A-5) Antibody
Chicken, Carp, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, C. elegans
ELISA, EM, Flo, ICC, IHC, IP, WB
Biotin Conjugated
200 µg/$523
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (APC) (C92F3A-5) Antibody
Chicken, Carp, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, C. elegans
ELISA, EM, Flo, ICC, IHC, IP, WB
APC Conjugated
200 µg/$528
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal Antibody
Xenopus, Chicken, Drosophila, Pig, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, C. elegans
Flo, IF, IHC, IP, WB
Unconjugated
50 µg/$503; 200 µg/$802
Select
HSP70 / Heat Shock Protein 70 Rabbit Polyclonal Antibody
Fish, Mammal, Plant
WB
Unconjugated
100 µg/$608
HSP70 / Heat Shock Protein 70 ELISA Kit
Select
Sandwich
96-Well Microplate
Chicken
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal Antibody
Xenopus, Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Human, Monkey
Flo, WB
Unconjugated
50 µg/$603; 200 µg/$1,001
HSP70 / Heat Shock Protein 70 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Human Monoclonal (5C3) Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
60 µl/$460
Select
HSP70 / Heat Shock Protein 70 Mouse anti-Bovine Monoclonal (Magnetic beads) (SJ-70) Antibody
Bovine, Human
IP
Magnetic beads Conjugated
100 µg/$399
Viewing 1-25 of 218 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).