Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.
Gene Name: | hydroxysteroid (17-beta) dehydrogenase 12 |
Synonyms: | HSD17B12, 17-beta-HSD 12, 17beta-HSD type 12, 3-ketoacyl-CoA reductase, KAR, SDR12C1, Steroid dehydrogenase homolog |
Target Sequences: | NM_016142 NP_057226.1 Q53GQ0 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.