HSD17B10 / HADH2

hydroxysteroid (17-beta) dehydrogenase 10

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

HSD17B10 / HADH2 (9)

Publications

No (9)

Tag

6His, N-terminus (1)

GST (1)

His-GST (1)

His-SUMO (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (2)

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Human HSD17B10 / HADH2 Protein (Recombinant His-SUMO) (Full Length) - LS-G21905

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

42.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse HSD17B10 / HADH2 Protein (Recombinant His-GST) (aa4-202) - LS-G25563

Source:

E. coli

Tag:

His-GST

Molecular Weight:

27.8 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Human HSD17B10 / HADH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78210

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.98 kDa

Price:

20 µg/$150

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Human HSD17B10 / HADH2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66651

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.8 kDa

Price:

20 µg/$1,107

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Human HSD17B10 / HADH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78211

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.92 kDa

Price:

20 µg/$150

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Rat HSD17B10 / HADH2 Protein (Recombinant 6His, N-terminus) (aa2-261) - LS-G57190

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human HSD17B10 / HADH2 Protein (Recombinant GST) (Full Length) - LS-G28790

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.3 kDa

Price:

10 µg/$479; 25 µg/$670

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HSD17B10 / HADH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100311

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.92 kDa

Price:

100 µg/$494

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HSD17B10 / HADH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120543

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.98 kDa

Price:

100 µg/$494

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