Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
HRAS / H-Ras
Harvey rat sarcoma viral oncogene homolog
HRAS / H-Ras belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
| Gene Name: | Harvey rat sarcoma viral oncogene homolog |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
| Synonyms: | HRAS, C-H-RAS, C-has/bas p21 protein, C-ras-Ki-2 activated oncogene, C-HA-RAS1, CTLO, H-ras, H-RASIDX, GTP- and GDP-binding peptide B, GTPase HRas, H-Ras-1, HAMSV, HRAS1, K-RAS, Ha-Ras, Ha-Ras1 proto-oncoprotein, Transforming protein p21, N-ras, p21ras, RASH1, C-BAS/HAS, C-ha-ras, p19 H-RasIDX protein |
| Target Sequences: | NM_005343 NP_005334.1 P01112 |
Publications (3)
1
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response. Swarbrick A, Roy E, Allen T, Bishop JM. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5402-7. (WB)
[PubMed:18378907]
[PMC:PMC2291136]
2
DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma. Zhao T, Bao Y, Gan X, Wang J, Chen Q, Dai Z, Liu B, Wang A, Sun S, Yang F, Wang L. Theranostics. 2019 August;9:6175-6190. [Full Text Article]
[PubMed:31534544]
[PMC:PMC6735520]
Related Antibodies: LS-C340614.
3
Single-cell in situ imaging of palmitoylation in fatty-acylated proteins. Xinxin Gao, Rami N Hannoush. Nature protocols. 2014 November;9:2607-23. [Full Text Article]
[PubMed:25299157]
Related Antibodies: LS-C165008.
☰ Filters
Products
Antibodies
(92)
Proteins
(16)
ELISA Kits
(6)
Type
Custom
(4)
Over-Expression Lysate
(7)
Primary
(92)
Recombinant
(9)
Sandwich
(2)
Target
HRAS / H-Ras
(114)
Reactivity
Human
(79)
Mouse
(41)
Rat
(29)
Chicken
(3)
Dog
(10)
Guinea pig
(2)
Hamster
(2)
Monkey
(9)
Rabbit
(2)
Xenopus
(2)
Application
IHC
(20)
IHC-Fr
(1)
IHC-P
(10)
WB
(86)
Flo
(1)
ELISA
(31)
ICC
(1)
IF
(20)
IP
(3)
Neut
(1)
Peptide-ELISA
(1)
Host
rabbit
(63)
mouse
(28)
rat
(1)
Product Group
IHCPlus
(2)
Isotype
IgG
(34)
IgG1
(19)
IgG1,k
(1)
IgG2b
(8)
Clonality
monoclonal mc
(29)
polyclonal pc
(63)
Clone
H-Ras-03
(1)
OTI1A1
(2)
OTI1C2
(2)
OTI1C8
(2)
OTI1D9
(2)
OTI1F2
(2)
OTI1G8
(2)
OTI1H3
(2)
OTI2A1
(2)
Format
96-Well Strip Plate
(6)
AP Conjugated
(1)
APC
(1)
APC Conjugated
(5)
Atto 390 Conjugated
(1)
Atto 488 Conjugated
(1)
Atto 594 Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(8)
Carrier-free
(8)
Cy3 Conjugated
(1)
Cy7 Conjugated
(1)
FITC Conjugated
(8)
HRP Conjugated
(7)
PE Conjugated
(5)
PerCP Conjugated
(1)
RPE Conjugated
(1)
Unconjugated
(51)
Epitope
aa82-176
(8)
aa151-179
(7)
N-Terminus
(1)
aa1-189
(1)
aa101-137
(1)
aa104-128
(1)
aa111-189
(1)
aa146-176
(1)
aa153-177
(1)
aa62-76
(1)
Publications
No
(112)
Yes
(2)
Sample Type
Plasma
(2)
Serum
(2)
Tissue Homogenates
(1)
Tag
6His, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(3)
His-T7
(1)
Myc-DDK (Flag)
(9)
Species
Human
(12)
Rat
(1)
Source
293T Cells
(4)
Baculovirus
(1)
E. coli
(4)
HEK 293 Cells
(5)
Wheat Germ Extract
(2)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(1)
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI1C8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI1D9) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (Carrier-free) (OTI1D9) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HRAS / H-Ras Rabbit anti-Human Polyclonal (aa146-176) Antibody
Mouse, Human
IF, WB
Unconjugated
400 µl/$393
HRAS / H-Ras Rat anti-Human Monoclonal (aa62-76) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, IP, Neut, WB
Unconjugated
50 µg/$890
E. coli
6His, N-terminus
24 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
HRAS / H-Ras Rabbit anti-Human Polyclonal (aa111-189) Antibody
Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
HRAS / H-Ras Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HRAS / H-Ras Mouse anti-Human Monoclonal (H-Ras-03) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$385
HRAS / H-Ras Rabbit anti-Human Polyclonal (aa151-179) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
HRAS / H-Ras Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI1G8) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI1C2) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (Carrier-free) (OTI1C2) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HRAS / H-Ras Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$351
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI2A1) Antibody
Mouse, Dog, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (Carrier-free) (OTI2A1) Antibody
Mouse, Dog, Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HRAS / H-Ras Mouse anti-Human Monoclonal (OTI1A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HRAS / H-Ras Mouse anti-Human Monoclonal (Carrier-free) (OTI1A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HRAS / H-Ras Rabbit anti-Human Polyclonal (aa104-128) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
HRAS / H-Ras Rabbit anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$801
Wheat Germ Extract
GST
46.42 kDa
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
18.7 kDa
20 µg/$150
HRAS / H-Ras Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25
of 114
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
