HPTPB / PTPRB

protein tyrosine phosphatase, receptor type, B

HPTPB / PTPRB is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

HPTPB / PTPRB (8)

Publications

No (8)

Tag

His (2)

His-SUMO (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Yeast (1)

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Human HPTPB / PTPRB Protein (Recombinant His) (aa1643-1997) - LS-G23093

Source:

Yeast

Tag:

His

Molecular Weight:

43.39 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Mouse HPTPB / PTPRB Protein (Recombinant His-T7) (aa1214-1463) - LS-G13262

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.2 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human HPTPB / PTPRB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78403

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

249 kDa

Price:

20 µg/$215

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HPTPB / PTPRB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124177

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

249 kDa

Price:

100 µg/$710

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Human HPTPB / PTPRB Protein (Recombinant His-SUMO) (aa1643-1997) - LS-G21100

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

57.36 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HPTPB / PTPRB Protein (Recombinant His-T7) (aa1655-1918) - LS-G13259

Source:

E. coli

Tag:

His-T7

Molecular Weight:

34.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Rat HPTPB / PTPRB Protein (Recombinant His) (aa1041-1310) - LS-G24191

Source:

E. coli

Tag:

His

Molecular Weight:

34.3 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human HPTPB / PTPRB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66741

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

249 kDa

Price:

20 µg/$1,107

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