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Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
Gene Name: | hypoxanthine phosphoribosyltransferase 1 |
Synonyms: | HPRT1, HGPRT, HGPRTase, HPRT |
Target Sequences: | NM_000194 NP_000185.1 P00492 |
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