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HOXB7 is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
Gene Name: | homeobox B7 |
Synonyms: | HOXB7, Homeo box c1 protein, Homeobox protein HHO.C1, Hox-2.3, Homeo box 2C, Homeobox B7, Homeobox protein Hox-B7, HHO.C1, Homeo box B7, Homeobox protein Hox-2C, HOX2, HOX2C |
Target Sequences: | NM_004502 NP_004493.3 P09629 |
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