HORMAD1

HORMA domain containing 1

Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.

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Products

ELISA Kits (1)

Type

Cell-Based (1)

Target

HORMAD1 (1)

Reactivity

Human (1)

Format

96-Well Microplate (1)

Publications

No (1)

Sample Type

Adherent Cell Cultures (1)

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Human HORMAD1 (Cell-Based ELISA) ELISA Kit - LS-F3247

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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