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HOMER1 / Homer 1
homer homolog 1 (Drosophila)
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.
| Gene Name: | homer homolog 1 (Drosophila) |
| Synonyms: | HOMER1, HOMER, Homer homolog 1 (Drosophila), Homer protein homolog 1, HOMER1B, SYN47, Ves-1, Homer-1, HOMER-1B, HOMER1A, HOMER1C |
| Target Sequences: | NM_004272 NP_004263.1 Q86YM7 |
Publications (5)
1
Exploring regulatory networks of miR-96 in the developing inner ear. Lewis MA, Buniello A, Hilton JM, Zhu F, Zhang WI, Evans S, van Dongen S, Enright AJ, Steel KP. Scientific reports. 2016 6:23363. (IHC; Mouse)
[Full Text Article]
[PubMed:26988146]
[PMC:PMC4796898]
Related Antibodies: LS-C30485.
2
Synaptic activity induces input-specific rearrangements in a targeted synaptic protein interaction network. Jonathan D Lautz, Emily A Brown, Alison A Williams VanSchoiack, Stephen E P Smith. Journal of neurochemistry. 2018 September;146:540-559. [Full Text Article]
[PubMed:29804286]
[PMC:PMC6150823]
Related Antibodies: LS-C103482.
3
Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility. Jonathan D Lautz, Edward P Gniffke, Emily A Brown, Karen B Immendorf, Ryan D Mendel, Stephen E P Smith. Scientific reports. 2019 July;9:10890. [Full Text Article]
[PubMed:31350430]
[PMC:PMC6659712]
Related Antibodies: LS-C103482.
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Antibodies
(41)
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(41)
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HOMER1 / Homer 1
(41)
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(40)
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(16)
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(41)
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(29)
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(25)
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(5)
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(2)
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(22)
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(4)
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(1)
Publications
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(39)
Yes
(2)
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa72-339) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (AT1F3) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa281-330) Antibody
Human
WB
Unconjugated
100 µl/$424
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$341
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
HOMER1 / Homer 1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa96-122) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa101-150) (HRP) Antibody
Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon, Orangutan
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa101-150) (Biotin) Antibody
Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon, Orangutan
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (aa101-150) (FITC) Antibody
Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon, Orangutan
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
0.1 ml/$386
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (aa1-354) (OTI7G10) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$434
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (aa1-354) (Carrier-free) (OTI7G10) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HOMER1 / Homer 1 Mouse anti-Human Monoclonal (aa1-354) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$586
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$332
HOMER1 / Homer 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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product results
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