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HNRPM / HNRNPM
heterogeneous nuclear ribonucleoprotein M
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
| Gene Name: | heterogeneous nuclear ribonucleoprotein M |
| Synonyms: | HNRNPM, CEA receptor, CEAR, HnRNA-binding protein M4, HNRNPM4, HNRPM4, N-acetylglucosamine receptor 1, NAGR1, HnRNP M, HNRPM, HTGR1 |
| Target Sequences: | NM_005968 NP_005959.2 P52272 |
Publications (3)
1
The clinical and prognostic correlation of HRNPM and SLC1A5 in pathogenesis and prognosis in epithelial ovarian cancer. Bjersand K, Seidal T, Sundström-Poromaa I, Åkerud H, Skirnisdottir I. PloS one. 2017 June;12:e0179363. (Human)
[Full Text Article]
[PubMed:28609484]
[PMC:PMC5469483]
Related Antibodies: LS-B4384.
2
Two distinct nuclear stress bodies containing different sets of RNA-binding proteins are formed with HSATIII architectural noncoding RNAs upon thermal stress exposure. Mahmoud Khamis Aly, Kensuke Ninomiya, Shungo Adachi, Tohru Natsume, Tetsuro Hirose. Biochemical and biophysical research communications. 2019 August;516:419-423. [Full Text Article]
[PubMed:31227213]
3
Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model. Tomonori Shibata, Konami Nagano, Morio Ueyama, Kensuke Ninomiya, Tetsuro Hirose, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani. Nature communications. 2021 January;12:236. [Full Text Article]
[PubMed:33431896]
[PMC:PMC7801683]
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HNRPM / HNRNPM
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(40)
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(1)
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(1)
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Purified
(1)
HNRPM / HNRNPM Mouse anti-Human Monoclonal (3F7) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$375
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HNRPM / HNRNPM Mouse anti-Human Monoclonal (5G6C11) Antibody
Mouse, Rat, Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µg/$459
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386
HNRPM / HNRNPM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
HNRPM / HNRNPM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µl/$305; 100 µl/$357
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (aa11-60) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (aa491-730) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$375
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (Pro43) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (OTI3F3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (Carrier-free) (OTI3F3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (OTI1E12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (Carrier-free) (OTI1E12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (OTI1F6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (Carrier-free) (OTI1F6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (OTI6H7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (Carrier-free) (OTI6H7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (OTI4C9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
HNRPM / HNRNPM Mouse anti-Human Monoclonal (aa1-261) (Carrier-free) (OTI4C9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HNRPM / HNRNPM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$305; 100 µl/$357
HNRPM / HNRNPM Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (aa21-50) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
HNRPM / HNRNPM Rabbit anti-Human Polyclonal (aa491-730) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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