HNE / Neutrophil Elastase

elastase, neutrophil expressed

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

☰ Filters

Products

Antibodies (60)

ELISA Kits (31)

Proteins (9)

Type

Competitive EIA (4)

Custom (1)

Native (1)

Over-Expression Lysate (2)

Primary (60)

Recombinant (6)

Sandwich (23)

Sandwich CLIA (3)

Target

HNE / Neutrophil Elastase (100)

Reactivity

Human (57)

Mouse (25)

Rat (9)

Dog (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Application

IHC (3)

IHC-P (4)

WB (38)

Flo (6)

EK (4)

ELISA (35)

ICC (9)

IE (3)

Inhb (4)

IP (8)

Peptide-ELISA (1)

RIA (1)

more less

Host

rabbit (37)

mouse (19)

goat (1)

sheep (3)

Product Group

IHCPlus (1)

PathPlus Cancer (2)

PathPlus Cancer Pathology (2)

Isotype

IgG (21)

IgG1 (13)

IgG1,k (1)

IgG2a,k (2)

IgG2b (1)

IgM (2)

Clonality

monoclonal mc (19)

polyclonal pc (41)

Clone

1A11 (1)

265-3K1 (1)

3B1 (1)

4E12 (1)

6B6B10 (1)

6B6G6 (1)

ELA 10-101.5 (1)

ELA 10-103.2 (1)

ELA 11-207.2 (1)

ELA 11-207.3 (1)

ELA10-101.5 (39A) (1)

more less

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (2)

96-Well Strip Plate (25)

APC (2)

APC Conjugated (4)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (5)

Preservative Free (1)

Unconjugated (29)

more less

Epitope

aa30-247 (8)

aa13-39 (7)

aa30-267 (4)

Publications

No (97)

Yes (3)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (2)

Cell Supernatant (2)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (27)

Serum (28)

Tissue Homogenates (5)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Select

PathPlus™ HNE / Neutrophil Elastase Antibody LS-B4244

Cancer Pathology

Cancer

(5.0) Rating

(1) Publication(s)

Antibody:

HNE / Neutrophil Elastase Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, IHC-P

Format:

Unconjugated

Price:

50 µg/$565

Select

PathPlus™ HNE / Neutrophil Elastase Antibody LS-B14135

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

HNE / Neutrophil Elastase Sheep anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

0.5 mg/$460

Select

HNE / Neutrophil Elastase Antibody LS-C781858

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

HNE / Neutrophil Elastase Antibody (HRP) LS-C23012

Antibody:

HNE / Neutrophil Elastase Sheep anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IE

Format:

HRP Conjugated

Price:

200 µg/$634

Select

HNE / Neutrophil Elastase Antibody (clone ELA10-101.5 (39A)) LS-C41872

Antibody:

HNE / Neutrophil Elastase Mouse anti-Human Monoclonal (ELA10-101.5 (39A)) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

0.2 mg/$471

Select

Pig HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F36096

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

Select

Monkey HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F43441

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

Select

Rat HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F20775

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F22767

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F11365

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Human HNE / Neutrophil Elastase Protein (Recombinant 6His, N-terminus) (aa30-267) - LS-G22905

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

27.5 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

Select

HNE / Neutrophil Elastase Antibody LS-C150762

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IE, WB

Format:

Unconjugated

Price:

1 ml/$493

Select

HNE / Neutrophil Elastase Antibody (aa13-39, Biotin) LS-C264260

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Human Polyclonal (aa13-39) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

Rat HNE / Neutrophil Elastase (CLIA) ELISA Kit - LS-F31099

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F4355

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.188 - 12 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

Select

HNE / Neutrophil Elastase Antibody LS-C663862

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

Select

HNE / Neutrophil Elastase Antibody (clone ELA 10-101.5) LS-C83032

Antibody:

HNE / Neutrophil Elastase Mouse anti-Human Monoclonal (ELA 10-101.5) Antibody

Reactivity:

Human

Applications:

EK, ELISA, Inhb

Format:

Unconjugated

Price:

100 µg/$372; 500 µg/$533

Select

HNE / Neutrophil Elastase Antibody LS-C488444

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

HNE / Neutrophil Elastase Antibody (clone 1A11) LS-C139254

Antibody:

HNE / Neutrophil Elastase Mouse anti-Human Monoclonal (1A11) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$423

Select

HNE / Neutrophil Elastase Antibody (aa30-247) LS-B16906

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Human Polyclonal (aa30-247) Antibody

Reactivity:

Human

Applications:

ICC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F39774

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$699

Select

Rat HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F4131

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

Select

HNE / Neutrophil Elastase Antibody LS-C662342

Antibody:

HNE / Neutrophil Elastase Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

IHC, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

HNE / Neutrophil Elastase Antibody LS-C128709

Antibody:

HNE / Neutrophil Elastase Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, RIA, WB

Format:

Unconjugated

Price:

20 µl/$473; 100 µl/$634

Select

HNE / Neutrophil Elastase Antibody (FITC) LS-C535648

Antibody:

HNE / Neutrophil Elastase Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

FITC Conjugated

Price:

100 µl/$951

Viewing 1-25 of 100 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.