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This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Gene Name: | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
Synonyms: | HMGCS1, HMG-CoA synthase, HMGCS |
Target Sequences: | NM_002130 NP_002121.4 Q01581 |
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