HMG-CoA Reductase / HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (31)

Type

Primary (31)

Target

HMG-CoA Reductase / HMGCR (31)

Reactivity

Human (23)

Mouse (10)

Rat (18)

Dog (3)

Monkey (1)

Pig (3)

Yeast (3)

Application

IHC (12)

IHC-P (2)

WB (25)

ELISA (5)

ICC (1)

IF (5)

IP (1)

Peptide-ELISA (2)

Host

rabbit (30)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (13)

Clonality

polyclonal pc (31)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (15)

Epitope

C-Terminus (8)

aa638-887 (8)

aa295-308 (1)

Publications

No (31)

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IHC-plus™ HMG-CoA Reductase / HMGCR Antibody LS-B16059

(4.0) Rating

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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HMG-CoA Reductase / HMGCR Antibody LS-C331599

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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HMG-CoA Reductase / HMGCR Antibody LS-C806211

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus) LS-B14015

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus, HRP) LS-C446440

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Human, Yeast

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus, Biotin) LS-C446438

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Human, Yeast

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus, FITC) LS-C446439

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Human, Yeast

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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HMG-CoA Reductase / HMGCR Antibody LS-C748368

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

HMG-CoA Reductase / HMGCR Antibody LS-C285529

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

HMG-CoA Reductase / HMGCR Antibody (HRP) LS-C318764

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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HMG-CoA Reductase / HMGCR Antibody (Biotin) LS-C317112

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

HMG-CoA Reductase / HMGCR Antibody (FITC) LS-C318761

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

HMG-CoA Reductase / HMGCR Antibody LS-C833882

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HMG-CoA Reductase / HMGCR Antibody LS-C749723

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

Select

HMG-CoA Reductase / HMGCR Antibody LS-C666166

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$331

Select

HMG-CoA Reductase / HMGCR Antibody LS-C833883

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HMG-CoA Reductase / HMGCR Antibody LS-C834991

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HMG-CoA Reductase / HMGCR Antibody (C-Terminus) LS-C345666

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

HMG-CoA Reductase / HMGCR Antibody (C-Terminus, HRP) LS-C480351

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

HMG-CoA Reductase / HMGCR Antibody (C-Terminus, Biotin) LS-C480349

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

HMG-CoA Reductase / HMGCR Antibody (C-Terminus, FITC) LS-C480350

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

HMG-CoA Reductase / HMGCR Antibody LS-C310626

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

100 µl/$749

Select

HMG-CoA Reductase / HMGCR Antibody (aa295-308) LS-C112813

Antibody:

HMG-CoA Reductase / HMGCR Goat anti-Human Polyclonal (aa295-308) Antibody

Reactivity:

Human, Monkey

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

Select

HMG-CoA Reductase / HMGCR Antibody (aa638-887) LS-C373178

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Rat Polyclonal (aa638-887) Antibody

Reactivity:

Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331

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HMG-CoA Reductase / HMGCR Antibody (aa638-887, HRP) LS-C712670

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Rat Polyclonal (aa638-887) (HRP) Antibody

Reactivity:

Rat

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$349; 200 µl/$408; 500 µl/$609; 1 ml/$762; 2 ml/$999; 5 ml/$1,729

• Unconjugated
• HRP

• Unconjugated
• HRP

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