HMG-CoA Reductase / HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Antibodies (31)

ELISA Kits (15)

Proteins (4)

Type

Competitive EIA (1)

Custom (2)

Primary (31)

Recombinant (4)

Sandwich (12)

Target

HMG-CoA Reductase / HMGCR (50)

Reactivity

Human (29)

Mouse (13)

Rat (22)

Bovine (1)

Dog (3)

Monkey (1)

Pig (4)

Yeast (3)

Application

IHC (12)

IHC-P (2)

WB (25)

ELISA (5)

ICC (1)

IF (5)

IP (1)

Peptide-ELISA (2)

Host

rabbit (30)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (13)

Clonality

polyclonal pc (31)

Format

96-Well Microplate (1)

96-Well Strip Plate (14)

APC (1)

APC Conjugated (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (15)

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Epitope

C-Terminus (8)

aa638-887 (8)

aa295-308 (1)

Publications

No (49)

Yes (1)

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Cell Lysates (2)

Plasma (11)

Serum (11)

Tissue Homogenates (6)

Tag

6His, N-terminus (1)

GST (1)

His (1)

His-T7 (1)

Species

Human (2)

Mouse (1)

Rat (1)

Source

E. coli (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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IHC-plus™ HMG-CoA Reductase / HMGCR Antibody LS-B16059

(4.0) Rating

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Rat HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F15758

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F32077

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Rat HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F36210

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Human HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F38082

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.63 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F11637

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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HMG-CoA Reductase / HMGCR Antibody LS-C331599

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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HMG-CoA Reductase / HMGCR Antibody LS-C806211

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F32591

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus) LS-B14015

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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HMG-CoA Reductase / HMGCR Antibody (C-Terminus, FITC) LS-C446439

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Human, Yeast

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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HMG-CoA Reductase / HMGCR Antibody LS-C748368

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

Rat HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F7315

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

Select

Mouse HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F15757

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Rat HMG-CoA Reductase / HMGCR (Sandwich ELISA) ELISA Kit - LS-F22322

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

HMG-CoA Reductase / HMGCR Antibody LS-C285529

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HMG-CoA Reductase / HMGCR Antibody (HRP) LS-C318764

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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HMG-CoA Reductase / HMGCR Antibody (Biotin) LS-C317112

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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HMG-CoA Reductase / HMGCR Antibody (FITC) LS-C318761

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

HMG-CoA Reductase / HMGCR Antibody LS-C833882

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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HMG-CoA Reductase / HMGCR Antibody LS-C749723

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

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HMG-CoA Reductase / HMGCR Antibody LS-C666166

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$331

Select

HMG-CoA Reductase / HMGCR Antibody LS-C833883

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HMG-CoA Reductase / HMGCR Antibody LS-C834991

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HMG-CoA Reductase / HMGCR Antibody (C-Terminus) LS-C345666

Antibody:

HMG-CoA Reductase / HMGCR Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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