HLA-DRB5

major histocompatibility complex, class II, DR beta 5

HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

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Products

Antibodies (18)

ELISA Kits (2)

Proteins (2)

Type

Competitive EIA (2)

Over-Expression Lysate (2)

Primary (18)

Target

HLA-DRB5 (22)

Reactivity

Human (20)

Mouse (1)

Rat (1)

Application

IHC (9)

IHC-P (1)

WB (17)

ELISA (7)

IP (1)

Host

rabbit (17)

mouse (1)

Isotype

IgG (16)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (17)

Clone

OTI4G7 (1)

Format

96-Well Strip Plate (2)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (8)

Epitope

aa43-70 (7)

aa30-266 (1)

Publications

No (22)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human HLA-DRB5 (Competitive EIA) ELISA Kit - LS-F11324

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human HLA-DRB5 (Competitive EIA) ELISA Kit - LS-F40096

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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HLA-DRB5 Antibody LS-C747812

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389

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HLA-DRB5 Antibody (aa43-70) LS-C321996

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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HLA-DRB5 Antibody (aa43-70, Biotin) LS-C258607

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HLA-DRB5 Antibody (aa43-70, FITC) LS-C258608

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HLA-DRB5 Antibody (aa43-70, APC) LS-C258606

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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HLA-DRB5 Antibody (aa43-70, PE) LS-C258610

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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HLA-DRB5 Antibody (aa43-70, Azide-free, HRP) LS-C258609

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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HLA-DRB5 Antibody (aa30-266, clone OTI4G7) LS-C827553

Antibody:

HLA-DRB5 Mouse anti-Human Monoclonal (aa30-266) (OTI4G7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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HLA-DRB5 Antibody (aa43-70) LS-C164922

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (aa43-70) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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HLA-DRB5 Antibody LS-C830477

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HLA-DRB5 Antibody LS-C311226

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$749

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HLA-DRB5 Antibody LS-C311227

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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HLA-DRB5 Antibody (HRP) LS-C542531

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

HLA-DRB5 Antibody (Biotin) LS-C522399

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

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HLA-DRB5 Antibody (FITC) LS-C532444

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

HLA-DRB5 Antibody (APC) LS-C514185

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

Select

HLA-DRB5 Antibody (PE) LS-C650645

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

HLA-DRB5 Antibody LS-C747811

Antibody:

HLA-DRB5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Human HLA-DRB5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G95107

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.06 kDa

Price:

20 µg/$150

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HLA-DRB5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118174

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.06 kDa

Price:

100 µg/$494

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