HLA-DR

MHC Class II HLA-DR

HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR and its ligand, a peptide of 9 amino acids in length or longer, constitutes a ligand for the T-cell receptor (TCR). HLA (human leukocyte antigens) were originally defined as cell surface antigens that mediate graft-versus-host disease, which resulted in the rejection of tissue transplants in HLA-mismatched donors. Identification of these antigens has led to greater success and longevity in organ transplant. HLA-DR is also involved in several autoimmune conditions, disease susceptibility and disease resistance. It is also closely linked to HLA-DQ and this linkage often makes it difficult to resolve the more causative factor in disease. HLA-DR molecules are upregulated in response to signalling. In the instance of an infection, the peptide (such as the staphylococcal enterotoxin I peptide) is bound into a DR molecule and presented to a few of a great many T-cell receptors found on T-helper cells. These cells then bind to antigens on the surface of B-cells stimulating B-cell proliferation.

HLA-DR Target Details

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Products

Antibodies (84)

Type

Primary (84)

Target

HLA-DR (84)

Reactivity

Human (83)

Mouse (2)

Baboon (1)

Bovine (3)

Canine (4)

Crab-eating macaque (1)

Dog (1)

Monkey (3)

Non-Human Primates (4)

Application

IHC (27)

IHC-Fr (13)

IHC-P (18)

WB (25)

Flo (68)

Func (4)

ICC (6)

IF (11)

IHC-IF (1)

IP (16)

Host

rabbit (10)

mouse (61)

rat (13)

Product Group

IHCPlus (4)

Isotype

IgG (11)

IgG1 (13)

IgG1,k (3)

IgG2a (23)

IgG2a,k (9)

IgG2b (2)

IgG2b,k (5)

IgG3 (10)

IgG3,k (5)

Clonality

monoclonal mc (72)

polyclonal pc (11)

recombinant monoclonal rmc (1)

Clone

169-1B5.2 (3)

19-26.1 or MB-26.1 (3)

423L (3)

BGX.24 (1)

Bra-14 (3)

Bra30 (1)

CR3/43 (2)

EDU-1 (2)

F3.3 (1)

HL-39 (4)

IPO-10 (2)

L243 (12)

LN3 (2)

LN-3 (1)

MEM-12 (10)

XM01 (2)

YD1/63.4.10 (5)

YE2/36-HLK (3)

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Format

APC Conjugated (5)

Azide-free (4)

Biotin Conjugated (6)

BSA-free (4)

Concentrated (1)

Cy5 Conjugated (1)

Cy7 Conjugated (1)

DY594 Conjugated (1)

FITC (1)

FITC Conjugated (11)

HRP Conjugated (3)

PE (3)

PE Conjugated (11)

PerCP Conjugated (4)

Preservative Free (2)

Ready-to-Use (3)

RPE Conjugated (2)

Unconjugated (39)

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Epitope

HLA class II (1)

Publications

No (82)

Yes (2)

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HLA-DR Antibody (clone L243) LS-C41093

(4.3) Rating

(4) Publication(s)

Antibody:

HLA-DR Mouse anti-Human Monoclonal (L243) Antibody

Reactivity:

Dog, Human, Monkey, Baboon

Applications:

Flo, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µg/$257

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IHC-plus™ HLA-DR Antibody (clone YE2/36-HLK) LS-B7229

(4.0) Rating

Antibody:

HLA-DR Rat anti-Human Monoclonal (YE2/36-HLK) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.125 mg/$460

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IHC-plus™ HLA-DR Antibody (clone LN-3, Concentrated) LS-B8114

(4.0) Rating

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Concentrated) (LN-3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated, Concentrated

Price:

0.25 ml/$495

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IHC-plus™ HLA-DR Antibody LS-B8929

(4.0) Rating

Antibody:

HLA-DR Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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IHC-plus™ HLA-DR Antibody (clone LN3) LS-B7879

(4.0) Rating

Antibody:

HLA-DR Mouse anti-Human Monoclonal (LN3) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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HLA-DR Antibody (clone LN3, PE, Cy7) LS-C107202

Antibody:

HLA-DR Mouse anti-Human Monoclonal (PE, Cy7) (LN3) Antibody

Reactivity:

Human

Applications:

Flo

Format:

PE, Cy7 Conjugated

Price:

25 Tests/$322; 100 Tests/$435

• Unconjugated
• PE, Cy7

• Unconjugated
• PE, Cy7

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HLA-DR Antibody LS-C24534

Antibody:

HLA-DR Rat anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

250 µg/$732

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HLA-DR Antibody (clone 169-1B5.2) LS-C390326

(4.0) Rating

(1) Publication(s)

Antibody:

HLA-DR Mouse anti-Human Monoclonal (169-1B5.2) Antibody

Reactivity:

Bovine, Human

Applications:

Flo, IF

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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HLA-DR Antibody (clone 169-1B5.2, Ready-to-Use) LS-C390335

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Ready-to-Use) (169-1B5.2) Antibody

Reactivity:

Bovine, Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Ready-to-Use

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HLA-DR Antibody (clone 19-26.1 or MB-26.1) LS-C390329

Antibody:

HLA-DR Mouse anti-Human Monoclonal (19-26.1 or MB-26.1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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HLA-DR Antibody (clone 19-26.1 or MB-26.1, Azide-free, BSA-free) LS-C390337

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Azide-free, BSA-free) (19-26.1 or MB-26.1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

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HLA-DR Antibody (clone 19-26.1 or MB-26.1, Ready-to-Use) LS-C390336

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Ready-to-Use) (19-26.1 or MB-26.1) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

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HLA-DR Antibody (Preservative Free) LS-C814866

Antibody:

HLA-DR Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human, Crab-eating macaque

Applications:

IHC-P, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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HLA-DR Antibody (clone YD1/63.4.10) LS-C27096

Antibody:

HLA-DR Rat anti-Human Monoclonal (YD1/63.4.10) Antibody

Reactivity:

Human

Applications:

Flo, IHC-Fr

Format:

Unconjugated

Price:

0.2 mg/$471

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HLA-DR Antibody (clone Bra30) LS-C347452

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Bra30) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.5 ml/$424

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HLA-DR Antibody (clone Bra-14) LS-C390315

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Bra-14) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

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HLA-DR Antibody (clone Bra-14, Ready-to-Use) LS-C390317

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Ready-to-Use) (Bra-14) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

Select

HLA-DR Antibody (clone Bra-14, Azide-free, BSA-free) LS-C390316

Antibody:

HLA-DR Mouse anti-Human Monoclonal (Azide-free, BSA-free) (Bra-14) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

• Unconjugated
• Unconjugated, Ready-to-Use
• Unconjugated, Azide-free, BSA-free

Select

HLA-DR Antibody (clone L243) LS-C763548

Antibody:

HLA-DR Mouse anti-Human Monoclonal (L243) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IP, WB

Format:

Unconjugated

Price:

25 µg/$218; 100 µg/$232

Select

HLA-DR Antibody LS-C835588

Antibody:

HLA-DR Mouse Monoclonal Antibody

Applications:

ICC, IHC, IHC-IF, WB

Format:

Unconjugated

Price:

10 µl/$299; 100 µl/$548

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HLA-DR Antibody (clone L243, FITC) LS-C204437

Antibody:

HLA-DR Mouse anti-Human Monoclonal (FITC) (L243) Antibody

Reactivity:

Canine, Human, Non-Human Primates

Applications:

Flo, Func, ICC, IHC-Fr, IHC-P, IP, WB

Format:

FITC Conjugated

Price:

100 Tests/$337

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HLA-DR Antibody (clone L243, APC) LS-C204408

Antibody:

HLA-DR Mouse anti-Human Monoclonal (APC) (L243) Antibody

Reactivity:

Canine, Human, Non-Human Primates

Applications:

Flo, Func, ICC, IHC-Fr, IHC-P, IP, WB

Format:

APC Conjugated

Price:

100 Tests/$365

Select

HLA-DR Antibody (clone L243, PE) LS-C204477

Antibody:

HLA-DR Mouse anti-Human Monoclonal (PE) (L243) Antibody

Reactivity:

Canine, Human, Non-Human Primates

Applications:

Flo, Func, ICC, IHC-Fr, IHC-P, IP, WB

Format:

PE Conjugated

Price:

100 Tests/$365

Select

HLA-DR Antibody (clone L243, PE, DY594) LS-C742360

Antibody:

HLA-DR Mouse anti-Human Monoclonal (PE, DY594) (L243) Antibody

Reactivity:

Canine, Human, Non-Human Primates

Applications:

Flo, Func, ICC, IHC-Fr, IHC-P, IP, WB

Format:

PE, DY594 Conjugated

Price:

100 Tests/$386

Select

HLA-DR Antibody LS-C24514

Antibody:

HLA-DR Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

200 µg/$732

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