order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
| Gene Name: | major histocompatibility complex, class II, DP alpha 1 |
| Synonyms: | HLA-DPA1, DP(W4), DP(W3), HLADP, HLA-SB alpha chain, MHC class II DPA1, HLASB, PLT1, MHC class II antigen, MHC class II DP3-alpha, HLA-DP1A, MHC class II HLA-DPA1 antigen |
| Target Sequences: | X03100 CAA26887.1 P20036 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
