HLA-A/B/C

MHC Class I HLA-A / HLA-B / HLA-C

The human leukocyte antigen (HLA) system is the locus of genes that encode for proteins on the surface of cells that are responsible for regulation of the immune system in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and has many other functions. The HLA genes are the human versions of the major histocompatibility complex (MHC) genes that are found in most vertebrates (and thus are the most studied of the MHC genes). The proteins encoded by certain genes are also known as antigens, as a result of their historic discovery as factors in organ transplants. The major HLAs are essential elements for immune function. Different classes have different functions: HLAs corresponding to MHC class I (A, B, and C) present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fragments of the virus to the surface of the cell so that the cell can be destroyed by the immune system. These peptides are produced from digested proteins that are broken down in the proteasomes. In general, these particular peptides are small polymers, about 9 amino acids in length. Foreign antigens presented by MHC class I attract killer T-cells (also called CD8 positive- or cytotoxic T-cells) that destroy cells.

HLA-A/B/C Target Details

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Products

Antibodies (64)

Type

Primary (64)

Target

HLA-A/B/C (64)

Reactivity

Human (60)

Mouse (4)

Rat (2)

Baboon (4)

Bovine (15)

Cat (6)

Cynomolgus (3)

Cynomolgus monkey (1)

Feline (5)

Macaque (2)

Monkey (4)

Non-Human Primates (7)

Primate (4)

Rabbit (1)

Rhesus monkey (1)

Shrew (2)

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Application

IHC (16)

IHC-Fr (15)

WB (21)

Flo (56)

Block (1)

Ctox (1)

ELISA (12)

Func (6)

ICC (6)

IF (10)

Inhb (1)

IP (26)

Peptide-ELISA (1)

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Host

rabbit (4)

mouse (54)

rat (6)

Product Group

IHCPlus (2)

Isotype

IgG (2)

IgG1 (5)

IgG1,k (1)

IgG2a (25)

IgG2a,k (18)

IgG2b (6)

IgG3 (5)

Clonality

monoclonal mc (60)

polyclonal pc (4)

Clone

246-B8.E7 (2)

MEM-123 (5)

MEM-147 (4)

W6/32 (30)

W6/32 HLK (4)

YTH862 (2)

YTH862.2 (1)

Format

AF488 Conjugated (1)

AF647 Conjugated (1)

APC Conjugated (1)

Azide-free (3)

Biotin Conjugated (7)

BSA-free (1)

Cy5 Conjugated (1)

Cy5.5 (1)

Cy5.5 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (7)

HRP Conjugated (3)

Low Endotoxin (4)

PE (3)

PE Conjugated (8)

PerCP Conjugated (3)

RPE Conjugated (1)

Unconjugated (29)

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Epitope

Internal (1)

aa204-253 (1)

Publications

No (62)

Yes (2)

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HLA-A/B/C Antibody (clone W6/32) LS-C190912

(4.0) Rating

(1) Publication(s)

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Bovine, Cat, Cynomolgus, Cynomolgus monkey, Rhesus monkey, Human, Monkey, Baboon

Applications:

Block, Flo, IF, IHC, Inhb, IP, WB

Format:

Unconjugated

Price:

100 µg/$449

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HLA-A/B/C Antibody (clone W6/32) LS-C41097

(4.3) Rating

(4) Publication(s)

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Bovine, Cat, Human, Monkey, Baboon

Applications:

Flo, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µg/$268

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HLA-A/B/C Antibody (clone W6/32, Low Endotoxin) LS-C45722

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Low Endotoxin) (W6/32) Antibody

Reactivity:

Bovine, Feline, Non-Human Primates, Human

Applications:

ELISA, Flo, Func, ICC, IHC, IHC-Fr, IP, WB

Format:

Unconjugated, Low Endotoxin

Price:

0.1 mg/$330

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HLA-A/B/C Antibody (clone W6/32, PE) LS-C46517

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (PE) (W6/32) Antibody

Reactivity:

Bovine, Feline, Non-Human Primates, Human

Applications:

ELISA, Flo, Func, ICC, IHC-Fr, IP, WB

Format:

PE Conjugated

Price:

0.1 mg/$435

• Unconjugated, Low Endotoxin
• PE

• Unconjugated, Low Endotoxin
• PE

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HLA-A/B/C Antibody (clone W6/32) LS-C34614

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Human

Applications:

Ctox, Flo

Format:

Unconjugated

Price:

500 µg/$442

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HLA-A/B/C Antibody (clone W6/32, Low Endotoxin) LS-C58529

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Low Endotoxin) (W6/32) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC-Fr, IP

Format:

Unconjugated, Low Endotoxin

Price:

0.5 mg/$641

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HLA-A/B/C Antibody (clone MEM-147) LS-C45854

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (MEM-147) Antibody

Reactivity:

Human

Applications:

Flo, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$309

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HLA-A/B/C Antibody (clone MEM-147, PE) LS-C46472

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (PE) (MEM-147) Antibody

Reactivity:

Human

Applications:

Flo, IP, WB

Format:

PE Conjugated

Price:

0.1 mg/$393

• Unconjugated
• PE

• Unconjugated
• PE

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HLA-A/B/C Antibody (clone W6/32 HLK, FITC) LS-C63033

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (FITC) (W6/32 HLK) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

100 µg/$357

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IHC-plus™ HLA-A/B/C Antibody (clone W6/32) LS-B10022

(4.0) Rating

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

50 µg/$375

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IHC-plus™ HLA-A/B/C Antibody (clone MEM-123) LS-B10024

(4.0) Rating

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (MEM-123) Antibody

Reactivity:

Bovine, Human, Non-Human Primates

Applications:

ELISA, Flo, IHC, IHC-Fr, IP

Format:

Unconjugated

Price:

0.05 mg/$460

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HLA-A/B/C Antibody (clone MEM-123, PE) LS-C46501

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (PE) (MEM-123) Antibody

Reactivity:

Bovine, Human, Non-Human Primates

Applications:

ELISA, Flo, IP

Format:

PE Conjugated

Price:

0.1 mg/$393

• Unconjugated
• PE

• Unconjugated
• PE

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HLA-A/B/C Antibody (clone YTH862) LS-C68094

Antibody:

HLA-A/B/C Rat anti-Human Monoclonal (YTH862) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr

Format:

Unconjugated

Price:

200 µg/$732

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HLA-A/B/C Antibody (FITC) LS-C536724

Antibody:

HLA-A/B/C Rat anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IP

Format:

FITC Conjugated

Price:

100 µl/$951

• Unconjugated
• FITC

• Unconjugated
• FITC

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HLA-A/B/C Antibody (aa204-253) LS-C199885

Antibody:

HLA-A/B/C Rabbit anti-Human Polyclonal (aa204-253) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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HLA-A/B/C Antibody (clone W6/32 HLK, Azide-free) LS-C63034

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Azide-free) (W6/32 HLK) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Azide-free

Price:

1 mg/$634

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HLA-A/B/C Antibody (clone W6/32 HLK, Biotin) LS-C63032

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Biotin) (W6/32 HLK) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Biotin Conjugated

Price:

100 µg/$339

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HLA-A/B/C Antibody LS-C754802

Antibody:

HLA-A/B/C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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HLA-A/B/C Antibody (clone W6/32) LS-C664202

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Bovine, Feline, Non-Human Primates, Human

Applications:

ELISA, Flo, Func, ICC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$330

Select

HLA-A/B/C Antibody (clone W6/32, HRP) LS-C58696

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (HRP) (W6/32) Antibody

Reactivity:

Human

Applications:

IHC-Fr

Format:

HRP Conjugated

Price:

0.1 mg/$328

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HLA-A/B/C Antibody (clone W6/32, Biotin) LS-C58528

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Biotin) (W6/32) Antibody

Reactivity:

Human

Applications:

Flo

Format:

Biotin Conjugated

Price:

100 µg/$305

Select

HLA-A/B/C Antibody (clone W6/32, FITC) LS-C58695

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (FITC) (W6/32) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

0.1 mg/$328

• HRP
• Biotin
• FITC

• HRP
• Biotin
• FITC

Select

HLA-A/B/C Antibody (Low Endotoxin) LS-C123773

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Low Endotoxin) Antibody

Reactivity:

Bovine, Cat, Shrew, Cynomolgus, Macaque, Human, Monkey, Baboon

Applications:

ELISA, Flo, IHC, IHC-Fr, IP

Format:

Unconjugated, Low Endotoxin

Price:

500 µg/$968

Select

HLA-A/B/C Antibody (clone W6/32) LS-C770024

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (W6/32) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IP, WB

Format:

Unconjugated

Price:

25 µg/$224; 100 µg/$251; 1 mg/$285; 5 mg/$481

Select

HLA-A/B/C Antibody (clone W6/32, Azide-free, Low Endotoxin) LS-C812200

Antibody:

HLA-A/B/C Mouse anti-Human Monoclonal (Azide-free, Low Endotoxin) (W6/32) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IP, WB

Format:

Unconjugated, Azide-free, Low Endotoxin

Price:

25 µg/$221; 100 µg/$236; 1 mg/$433; 5 mg/$496

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