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HK2 / Hexokinase 2
hexokinase 2
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
| Gene Name: | hexokinase 2 |
| Family/Subfamily: | Non-protein Kinase , Hexokinase |
| Synonyms: | HK2, Hexokinase II, Hexokinase type II, Hexokinase-2, muscle, HK II, HXK2, Hexokinase-2, Muscle form hexokinase, Hexokinase 2, HKII, Hxk 2 |
| Target Sequences: | NM_000189 NP_000180.2 P52789 |
Publications (2)
1
p53 Protects Cells from Death at the Heatstroke Threshold Temperature. Lu Gong, Qinghe Zhang, Xiao Pan, Shuming Chen, Lina Yang, Bin Liu, Weijun Yang, Luyang Yu, Zhi-Xiong Xiao, Xin-Hua Feng, Haihe Wang, Zhi-Min Yuan, Jinrong Peng, Wei-Qiang Tan, Jun Chen. Cell reports. 2019 Dec;29:3693-3707e5. [Full Text Article]
[PubMed:31825845]
Related Antibodies: LS-B3571.
2
Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth. Li Zhou, Xinfang Yu, Ming Li, Guanghui Gong, Wenbin Liu, Tian Li, Huilan Zuo, Wei Li, Feng Gao, Haidan Liu. EBioMedicine. 2020 Jan;51:102570. [Full Text Article]
[PubMed:31806563]
[PMC:PMC7000337]
Related Antibodies: LS-C404653.
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HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa74-123) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal (OTI4C5) Antibody
Dog, Human
Flo, IF, WB
Unconjugated
100 µl/$450
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI4C5) Antibody
Dog, Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
E. coli
His
Biologically active
100 µg/$511; 500 µg/$1,348; 20 µg/$311
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal (3D3) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa401-431) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Human, Monkey
ELISA, IP, WB
Unconjugated
100 µl/$688
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal (3D3) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$541
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Pig, Human
WB
Unconjugated
50 µg/$332; 100 µg/$406; 200 µg/$505
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa91-121) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa401-431) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa401-431) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa401-431) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa401-431) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal (aa469-669) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
HK2 / Hexokinase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
HK2 / Hexokinase 2 Mouse anti-Human Monoclonal (4H1) Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$423
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