Histone

Histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation. Without histones, the unwound DNA in chromosomes would be very long (a length to width ratio of more than 10 million to 1 in human DNA). For example, each human cell has about 1.8 meters of DNA, (~6 ft) but wound on the histones it has about 90 micrometers (0.09 mm) of chromatin, which, when duplicated and condensed during mitosis, result in about 120 micrometers of chromosomes. Five major families of histones exist: H1/H5, H2A, H2B, H3 and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones.

Histone Target Details

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Products

Antibodies (42)

Type

Primary (42)

Target

Histone (42)

Reactivity

Human (41)

Mouse (6)

Rat (12)

All species (8)

Bovine (16)

Hamster (5)

Opossum (5)

Xenopus (5)

Application

IHC (13)

IHC-P (8)

WB (40)

Flo (6)

ELISA (13)

ICC (22)

IF (6)

IP (23)

Host

rabbit (16)

mouse (19)

sheep (7)

Product Group

IHCPlus (2)

Isotype

IgG (6)

IgG1 (8)

IgG2a,k (11)

Clonality

monoclonal mc (19)

polyclonal pc (23)

Clone

1415-1 (3)

6D10H9 (2)

AE-4 (3)

Format

APC (2)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (6)

BSA-free (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (5)

Preservative Free (1)

Ready-to-Use (2)

Unconjugated (12)

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Publications

No (42)

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Histone Antibody LS-B15279

Antibody:

Histone Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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Histone Antibody LS-C68011

Antibody:

Histone Mouse Monoclonal Antibody

Reactivity:

Rat, Human

Applications:

ICC, IHC, WB

Format:

Unconjugated

Price:

100 µg/$947

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Histone Antibody (HRP) LS-C546833

Antibody:

Histone Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Xenopus, Bovine, Rat, Opossum, Hamster, Human

Applications:

ICC, IHC, WB

Format:

HRP Conjugated

Price:

100 µl/$1,154

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Histone Antibody (Biotin) LS-C526726

Antibody:

Histone Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Xenopus, Bovine, Rat, Opossum, Hamster, Human

Applications:

ICC, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,154

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Histone Antibody (FITC) LS-C536709

Antibody:

Histone Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Xenopus, Bovine, Rat, Opossum, Hamster, Human

Applications:

ICC, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$1,154

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Histone Antibody (PE) LS-C654884

Antibody:

Histone Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Xenopus, Bovine, Rat, Opossum, Hamster, Human

Applications:

ICC, IHC, WB

Format:

PE Conjugated

Price:

100 µl/$1,154

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Histone Antibody (APC) LS-C517326

Antibody:

Histone Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Xenopus, Bovine, Rat, Opossum, Hamster, Human

Applications:

ICC, IHC, WB

Format:

APC Conjugated

Price:

100 µl/$1,154

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

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Histone Antibody LS-C24290

Antibody:

Histone Sheep anti-Bovine Polyclonal Antibody

Reactivity:

Bovine, Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

250 µg/$755

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Histone Antibody LS-B15859

Antibody:

Histone Rabbit Polyclonal Antibody

Reactivity:

All species, Human

Applications:

ICC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$375

Select

Histone Antibody (clone 6D10H9) LS-C343380

Antibody:

Histone Mouse anti-Human Monoclonal (6D10H9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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Histone Antibody (clone 6D10H9, Preservative Free, Biotin) LS-C343289

Antibody:

Histone Mouse anti-Human Monoclonal (Preservative Free) (Biotin) (6D10H9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated, Preservative Free

Price:

50 µg/$343

• Unconjugated
• Biotin, Preservative Free

• Unconjugated
• Biotin, Preservative Free

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Histone Antibody (clone AE-4) LS-C390250

Antibody:

Histone Mouse anti-Human Monoclonal (AE-4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

Select

Histone Antibody (clone AE-4, Azide-free, BSA-free) LS-C390252

Antibody:

Histone Mouse anti-Human Monoclonal (Azide-free, BSA-free) (AE-4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

Select

Histone Antibody (clone AE-4, Ready-to-Use) LS-C390272

Antibody:

Histone Mouse anti-Human Monoclonal (Ready-to-Use) (AE-4) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

Select

Histone Antibody (clone 1415-1) LS-C390265

Antibody:

Histone Mouse anti-Human Monoclonal (1415-1) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

20 µg/$371; 100 µg/$574

Select

Histone Antibody (clone 1415-1, Azide-free, BSA-free) LS-C390270

Antibody:

Histone Mouse anti-Human Monoclonal (Azide-free, BSA-free) (1415-1) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated, Azide-free, BSA-free

Price:

100 µg/$574

Select

Histone Antibody (clone 1415-1, Ready-to-Use) LS-C390267

Antibody:

Histone Mouse anti-Human Monoclonal (Ready-to-Use) (1415-1) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

7 ml/$574

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Azide-free, BSA-free
• Unconjugated, Ready-to-Use

Select

Histone Antibody (HRP) LS-C714864

Antibody:

Histone Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757

Select

Histone Antibody (Biotin) LS-C301208

Antibody:

Histone Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487

Select

Histone Antibody (FITC) LS-C696839

Antibody:

Histone Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$362; 200 µl/$427; 500 µl/$666; 1 ml/$826; 2 ml/$1,067; 5 ml/$1,892

Select

Histone Antibody (Cy3) LS-C705852

Antibody:

Histone Rabbit anti-Human Polyclonal (Cy3) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Cy3 Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

Select

Histone Antibody (PE) LS-C728934

Antibody:

Histone Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

PE Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

• HRP
• Biotin
• FITC
• Cy3
• PE

• HRP
• Biotin
• FITC
• More...
  • Cy3
  • PE

Select

Histone Antibody (HRP) LS-C714865

Antibody:

Histone Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

All species, Human

Applications:

ICC, IP, WB

Format:

HRP Conjugated

Price:

100 µl/$371; 200 µl/$439; 500 µl/$705; 1 ml/$864; 2 ml/$1,112; 5 ml/$2,003

Select

Histone Antibody (FITC) LS-C696837

Antibody:

Histone Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

All species, Human

Applications:

ICC, IP, WB

Format:

FITC Conjugated

Price:

100 µl/$383; 200 µl/$457; 500 µl/$758; 1 ml/$915; 2 ml/$1,173; 5 ml/$2,157

Select

Histone Antibody (Cy3) LS-C705848

Antibody:

Histone Rabbit anti-Human Polyclonal (Cy3) Antibody

Reactivity:

All species, Human

Applications:

ICC, IP, WB

Format:

Cy3 Conjugated

Price:

100 µl/$457; 200 µl/$563; 500 µl/$1,013; 1 ml/$1,190; 2 ml/$1,644; 5 ml/$3,081

• HRP
• FITC
• Cy3

• HRP
• FITC
• Cy3

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