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Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Gene Name: | huntingtin interacting protein 1 related |
Synonyms: | HIP1R, HIP1-related protein, HIP-12, KIAA0655, HIP12, HIP3, ILWEQ |
Target Sequences: | AB013384 BAA33713.1 O75146 |
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