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HFE2 / Hemojuvelin

hemochromatosis type 2 (juvenile)

HFE2 / Hemojuvelin is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

Gene Name: hemochromatosis type 2 (juvenile)
Synonyms: HFE2, Haemojuvelin, HFE2A, HJV, Hemochromatosis type 2 protein, Repulsive guidance molecule c, RGM domain family member C, Hemojuvelin, JH, RGMC
Target Sequences: NP_973733.1 Q6ZVN8

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (4)
Recombinant (8)
HFE2 / Hemojuvelin (12)
No (12)
Fc (1)
GST, N-terminus (1)
His (2)
His-GST, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (4)
Human (10)
293T Cells (2)
Baculovirus (1)
E. coli (4)
HEK 293 Cells (3)
Human (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
HFE2 / Hemojuvelin Protein - Recombinant Hemojuvelin By SDS-PAGE
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E. coli
His-T7
43.5 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
HFE2 / Hemojuvelin Protein - Eukaryotic Hemojuvelin By SDS-PAGE
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Human
None
66.1kDa
50 µg/$882; 10 µg/$352; 200 µg/$1,529; 100 µg/$1,303; 1 mg/$2,845; 500 µg/$2,341; 5 mg/$6,161; 2 mg/$3,287
HFE2 / Hemojuvelin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HFE2 / Hemojuvelin Protein - Recombinant Hemojuvelin By SDS-PAGE
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E. coli
His
22 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
HFE2 / Hemojuvelin Protein - Recombinant Hemojuvelin By SDS-PAGE
Select
E. coli
His-T7
40.4 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
HEK 293 Cells
Fc
66.1 kDa
10 µg/$442; 50 µg/$882; 100 µg/$1,242
HFE2 / Hemojuvelin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.3 kDa
100 µg/$494
HFE2 / Hemojuvelin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
33.5 kDa
20 µg/$150
HFE2 / Hemojuvelin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.3 kDa
20 µg/$150
HFE2 / Hemojuvelin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
33.5 kDa
100 µg/$494
HFE2 / Hemojuvelin Protein - Recombinant Hemojuvelin (HJV) by SDS-PAGE
Select
E. coli
His-GST, N-terminus
47.4kDa
10 µg/$259; 50 µg/$331; 200 µg/$602; 100 µg/$482; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
40 kDa
100 µg/$721
Viewing 1-12 of 12 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).