Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
With DHDDS, forms the dehydrodolichyl diphosphate syntase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.
Gene Name: | dehydrodolichyl diphosphate synthase |
Synonyms: | DHDDS, Cis-IPTase, Cis-isoprenyltransferase, Dedol-PP synthase, CPT, Cis-prenyl transferase, DS, HDS, RP59 |
Target Sequences: | NM_024887 NP_079163.2 Q86SQ9 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.