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Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Gene Name: | histone deacetylase 11 |
Family/Subfamily: | Histone Deacetylase , not assigned-Histone Deacetylase |
Synonyms: | HDAC11, HD11, Histone deacetylase 11 |
Target Sequences: | NM_024827 NP_079103.2 Q96DB2 |
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