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HBEGF / HB EGF
heparin-binding EGF-like growth factor
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
| Gene Name: | heparin-binding EGF-like growth factor |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | HBEGF, Dtr, DTS, DTSF, HEGFL, Diphtheria Toxin Receptor |
| Target Sequences: | NM_001945 NP_001936.1 Q99075 |
Publications (1)
1
Heparin-binding EGF-like growth factor (HB-EGF) antisense oligonucleotide protected against hyperlipidemia-associated atherosclerosis. S Kim, M J Graham, R G Lee, L Yang, S Kim, V Subramanian, J D Layne, L Cai, R E Temel, D Shih, A J Lusis, J A Berliner, S Lee. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2019 March;29:306-315. [Full Text Article]
[PubMed:30738642]
[PMC:PMC6452438]
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(47)
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HBEGF / HB EGF
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(39)
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(3)
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(22)
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(47)
HBEGF / HB EGF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HBEGF / HB EGF Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
HBEGF / HB EGF Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
HBEGF / HB EGF Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) Antibody
Human
WB
Unconjugated
400 µl/$393
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa21-160) Antibody
Human
WB
Unconjugated
100 µl/$289; 200 µl/$323; 500 µl/$435; 1 ml/$491; 2 ml/$605; 5 ml/$1,045
HBEGF / HB EGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
HBEGF / HB EGF Mouse anti-Human Monoclonal (aa63-148) Antibody
Human
ELISA, Neut, WB
Unconjugated
100 µg/$930
HBEGF / HB EGF Rabbit anti-Mouse Polyclonal (aa25-160) Antibody
Mouse
WB
Unconjugated
100 µl/$291; 200 µl/$326; 500 µl/$441; 1 ml/$499; 2 ml/$622; 5 ml/$1,067
HBEGF / HB EGF Rabbit anti-Mouse Polyclonal (aa25-160) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$372; 200 µl/$441; 500 µl/$709; 1 ml/$869; 2 ml/$1,118; 5 ml/$2,017
HBEGF / HB EGF Rabbit anti-Mouse Polyclonal (aa25-160) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$372; 200 µl/$441; 500 µl/$709; 1 ml/$869; 2 ml/$1,118; 5 ml/$2,017
HBEGF / HB EGF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
HBEGF / HB EGF Rabbit anti-Human Polyclonal (aa68-96) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
HBEGF / HB EGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
HBEGF / HB EGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HBEGF / HB EGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
HBEGF / HB EGF Mouse anti-Human Monoclonal (aa20-208) (OTI6F4) Antibody
Human
WB
Unconjugated
100 µl/$434
HBEGF / HB EGF Mouse anti-Human Monoclonal (aa20-208) (Carrier-free) (OTI6F4) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
HBEGF / HB EGF Mouse anti-Human Monoclonal (aa20-208) (Carrier-free) (OTI10B1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
HBEGF / HB EGF Mouse anti-Human Monoclonal (aa20-208) (Carrier-free) (OTI8B5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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