HBcAg / HBV Core Antigen

Hepatitis B Virus (HBV) Core Antigen (HBcAg)

HBcAg (core antigen) is a hepatitis B viral protein. HBeAg is the extracellular form of HBcAg, hence why the presence of both are markers of viral replication, and antibodies to these antigens are markers of a decline in replication. Both HBeAg and HBcAg are made from the same reading frame, but HBeAg is secreted from cells and accumulates in serum as an immunologically distinct soluble antigen. HBeAg is secreted and found in the serum of patients and serves as a marker of active replication in chronic hepatitis. Although the function of HBeAg is not clearly understood, one study demonstrated that it downregulated Toll-like receptor 2 expression on hepatocytes and monocytes leading to a decrease in cytokine expression. HBeAg is dispensable for replication, as mutant viruses with defects in the pre-C region are both infectious and pathogenic.

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Proteins (5)

Type

Recombinant (5)

Target

HBcAg / HBV Core Antigen (5)

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Hepatitis (5)

Hepatitis B (5)

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No (5)

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His (1)

Species

Hepatitis B Virus (2)

Virus (3)

Source

E. coli (1)

Yeast (1)

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Hepatitis B Virus HBcAg / HBV Core Antigen Protein (Recombinant) - LS-G37630

Source:

E. coli

Tag:

None

Molecular Weight:

18 kD

Price:

0.1 mg/$620

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Hepatitis B Virus HBcAg / HBV Core Antigen Protein (Recombinant His) (Full Length) - LS-G23219

Source:

Yeast

Tag:

His

Molecular Weight:

23 kD

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Virus HBcAg / HBV Core Antigen Protein (Recombinant) - LS-G37559

Tag:

None

Molecular Weight:

18 kDa

Price:

50 µg/$366

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Virus HBcAg / HBV Core Antigen Protein (Recombinant) - LS-G37629

Tag:

None

Molecular Weight:

25 kDa

Price:

0.1 mg/$933

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Virus HBcAg / HBV Core Antigen Protein (Recombinant) - LS-G37632

Tag:

None

Molecular Weight:

23 kDa

Price:

0.1 mg/$725

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