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HBcAg / HBV Core Antigen
Hepatitis B Virus (HBV) Core Antigen (HBcAg)
HBcAg (core antigen) is a hepatitis B viral protein. HBeAg is the extracellular form of HBcAg, hence why the presence of both are markers of viral replication, and antibodies to these antigens are markers of a decline in replication. Both HBeAg and HBcAg are made from the same reading frame, but HBeAg is secreted from cells and accumulates in serum as an immunologically distinct soluble antigen. HBeAg is secreted and found in the serum of patients and serves as a marker of active replication in chronic hepatitis. Although the function of HBeAg is not clearly understood, one study demonstrated that it downregulated Toll-like receptor 2 expression on hepatocytes and monocytes leading to a decrease in cytokine expression. HBeAg is dispensable for replication, as mutant viruses with defects in the pre-C region are both infectious and pathogenic.
| Gene Name: | Hepatitis B Virus (HBV) Core Antigen (HBcAg) |
| Family/Subfamily: | Virion Structure |
| Synonyms: | HBcAg |
| Target Sequences: | Q89714 |
Publications (1)
1
Parenteral-Oral Immunization with Plant-Derived HBcAg as a Potential Therapeutic Vaccine against Chronic Hepatitis B. Marcin Pyrski, Adam Aron Mieloch, Adam Plewinski, Aneta Basinska-Barczak, Aleksandra Gryciuk, Piotr Bociag, Marek Murias, Jakub Dalibor Rybka, Tomasz Pniewski. Vaccines. 2019 Dec;7:211. [Full Text Article]
[PubMed:31835350]
[PMC:PMC6963566]
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(11)
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HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa70-80) Antibody
Hepatitis B Virus
ELISA, ICC, IF, IHC, IP, WB
Unconjugated
100 µl/$848
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa70-80) (C1) Antibody
Hepatitis B Virus
ELISA, IF, IHC, WB
Unconjugated
100 µg/$583
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (HRP) Antibody
Hepatitis B Virus
ELISA, IHC, WB
HRP Conjugated
100 µl/$801
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (Biotin) Antibody
Hepatitis B Virus
ELISA, IF, IHC, WB
Biotin Conjugated
100 µl/$801
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (FITC) Antibody
Hepatitis B Virus
ELISA, IF, IHC, WB
FITC Conjugated
100 µl/$801
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (PE) Antibody
Hepatitis B Virus
ELISA, IF, IHC, WB
PE Conjugated
100 µl/$801
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (APC) Antibody
Hepatitis B Virus
ELISA, IF, IHC, WB
APC Conjugated
100 µl/$801
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (N-Terminus) Antibody
Hepatitis B Virus
ELISA, IHC, IP, WB
Unconjugated
100 µg/$567; 1 mg/$1,079
HBcAg / HBV Core Antigen Rabbit anti-Hepatitis B Virus Polyclonal Antibody
Human
ICC, IHC
Unconjugated
500 µl/$413; 1 ml/$623
HBcAg / HBV Core Antigen Rabbit anti-Hepatitis B Virus Polyclonal Antibody
Human
IHC
Unconjugated
0.5 ml/$328
HBcAg / HBV Core Antigen Rabbit anti-Hepatitis B Virus Polyclonal Antibody
Hepatitis B Virus
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$332; 0.5 ml/$506; 1 ml/$662
HBcAg / HBV Core Antigen Rabbit anti-Hepatitis B Virus Polyclonal (Ready-to-Use) Antibody
Hepatitis B Virus
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$314; 7 ml/$354; 15 ml/$488
HBcAg / HBV Core Antigen Mouse anti-Virus Monoclonal (H50) Antibody
Virus
IF
Unconjugated
0.2 mg/$486
HBcAg / HBV Core Antigen Mouse anti-Virus Monoclonal (Hep2 (H69)) Antibody
Virus
IF
Unconjugated
0.2 mg/$486
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa135-140) Antibody
Hepatitis B Virus
ELISA, ICC, IF, IHC, WB
Unconjugated
100 µl/$848
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa80) Antibody
Hepatitis B Virus
ELISA, Flo, IHC, IP
Unconjugated
100 µg/$567; 1 mg/$1,079
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa130-140) Antibody
Hepatitis B Virus
ELISA, IHC, IP, WB
Unconjugated
100 µl/$576
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal Antibody
Hepatitis B Virus
ELISA, IP, WB
Unconjugated
100 µg/$567; 1 mg/$1,079
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal Antibody
Hepatitis B Virus
ELISA
Unconjugated
1 mg/$1,154
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa138-145) Antibody
Hepatitis B Virus
ELISA, Flo, IHC, IP
Unconjugated
100 µg/$567; 1 mg/$1,079
E. coli
None
18 kD
0.1 mg/$620
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal Antibody
Hepatitis B Virus
ELISA, WB
Unconjugated
500 µg/$702
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (H3A4) Antibody
Hepatitis B Virus
ELISA, WB
Unconjugated
0.2 mg/$407; 0.5 mg/$487
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (H6F5) Antibody
Hepatitis B Virus
ELISA, WB
Unconjugated
0.2 mg/$407; 0.5 mg/$487
HBcAg / HBV Core Antigen Mouse anti-Hepatitis B Virus Monoclonal (aa135-140) (Biotin) Antibody
Hepatitis B Virus
ELISA, IP, WB
Biotin Conjugated
100 µg/$832
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