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The hemoglobin alpha 1 and alpha 2 (HBA1, HBA2) genes are subunits of adult Hemoglobin A protein with identical coding sequences. These subunits make up HbA (alongside two additional beta chains), which in normal adult life comprises about 97% of the total hemoglobin. Alpha chains combine with delta chains to constitute HbA-2, which together with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Deletions of hemoglobin alpha genes results in the blood disorder alpha-thalassemias.
Target Name: | Hemoglobin Alpha (HBA1/HBA2) |
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