HAVCR2 / TIM-3

hepatitis A virus cellular receptor 2

HAVCR2 / TIM-3 belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

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Products

Proteins (45)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (41)

Target

HAVCR2 / TIM-3 (45)

Application

SDS-PAGE (4)

Publications

No (45)

Tag

6His, C-terminus (5)

6His, N-terminus (1)

8His, N-terminus (1)

AVI-Fc, C-terminus (1)

DDK (Flag)-His, C-terminus (1)

Fc (1)

Fc, C-terminus (6)

Fc/6His,C-terminus (1)

Fc-6His, C-terminus (1)

Fc-AVI, C-terminus (1)

GST (1)

His (3)

His, N-Terminal (5)

His,C-terminus (5)

His,N-terminus (1)

His-T7 (1)

Human IgG Fc, C-terminus (2)

Human IgG1 Fc (2)

mFc, C-terminus (1)

Mouse IgG2 Fc (1)

Mouse IgG2a Fc, N-terminus (1)

Myc-DDK (Flag) (2)

more less

Species

Crab-eating macaque (2)

Cynomolgus (2)

Human (25)

Marmoset (2)

Mouse (13)

Source

293T Cells (1)

CHO Cells (3)

E. coli (4)

HEK 293 Cells (12)

Human Cells (10)

Mammalian Cells (13)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (15)

Supernatant (1)

Low Endotoxin Level

Low endotoxin level (32)

Biologically Active

Biologically active (3)

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Human HAVCR2 / TIM-3 Protein (Recombinant His, N-Terminal) - LS-G2093

Source:

E. coli

Tag:

His, N-Terminal

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human HAVCR2 / TIM-3 Protein (Recombinant 6His, C-terminus) (Ser22-Arg200) - LS-G38879

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.86kD

Price:

10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157

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Human HAVCR2 / TIM-3 Protein (Recombinant Mouse IgG2 Fc) (aa22-200) - LS-G4072

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$519

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Human HAVCR2 / TIM-3 Protein (Recombinant His,C-terminus) (Met1-Arg200) - LS-G48055

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human HAVCR2 consists of 190 amino acids and predicts a molecular mass of 21.3 kDa.

Price:

100 µg/$480; 1 mg/$2,324

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Human HAVCR2 / TIM-3 Protein (Recombinant His) (Met1-Arg200) - LS-G97947

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.4 kDa

Price:

100 µg/$843; 1 mg/$5,007

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Human HAVCR2 / TIM-3 Protein (Recombinant Human IgG1 Fc) (aa22-200) - LS-G4061

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$519

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Cynomolgus HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) (Ser22-Arg201) - LS-G40378

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.3kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Mouse HAVCR2 / TIM-3 Protein (Recombinant 6His, C-terminus) (Arg20-Ala193) - LS-G40112

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.9kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Mouse HAVCR2 / TIM-3 Protein (Recombinant 6His, C-terminus) (Arg20-Arg191) - LS-G40199

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.2kD

Price:

10 µg/$266; 50 µg/$343; 500 µg/$1,377; 1 mg/$1,765

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) (Arg20-Arg191) - LS-G40154

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.3kD

Price:

10 µg/$266; 50 µg/$343; 500 µg/$1,377; 1 mg/$1,765

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Human HAVCR2 / TIM-3 Protein (Recombinant GST) (Full Length) - LS-G35843

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.36 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Arg191) - LS-G49185

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse HAVCR2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 411 amino acids and has a predicted molecular mass of 45.9 kDa. The apparent molecular mass of the protein is approximately 58-66 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human HAVCR2 / TIM-3 Protein (Recombinant Fc-6His, C-terminus) (Ser22-Arg200) - LS-G39505

Source:

Human Cells

Tag:

Fc-6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.7kD

Price:

10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157

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Mouse HAVCR2 / TIM-3 Protein (Recombinant His) (Met1-Arg191) - LS-G98169

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.3 kDa

Price:

100 µg/$721

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Fc) (Met1-Arg191) - LS-G98171

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.9 kDa

Price:

100 µg/$721

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Human HAVCR2 / TIM-3 Protein (Over-Expression Lysate His, N-Terminal) (Ser22-Gly202) - LS-G96984

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~20 kDa

Price:

100 µg/$298

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Human HAVCR2 / TIM-3 Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Ser22-Gly202) - LS-G96985

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~20 kDa

Price:

200 µl/$283

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Human HAVCR2 / TIM-3 Protein (Recombinant His, N-Terminal) (Ser22-Gly202) - LS-G96987

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~20 kDa (30-40 kDa reducing conditions)

Price:

10 µg/$289; 100 µg/$432; 50 µg/$360

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Human HAVCR2 / TIM-3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85542

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

20 µg/$150

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HAVCR2 / TIM-3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102083

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

100 µg/$494

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Marmoset HAVCR2 / TIM-3 Protein (Recombinant 6His, C-terminus) (Glu24-Ile193) - LS-G40209

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.7kD

Price:

10 µg/$266; 50 µg/$343; 500 µg/$1,377; 1 mg/$1,765

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Human HAVCR2 / TIM-3 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Arg200) - LS-G141217

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human HAVCR2 consists of 417 amino acids and predicts a molecular mass of 46.6 kDa.

Price:

100 µg/$441; 1 mg/$2,003

Select

Mouse HAVCR2 / TIM-3 Protein (Recombinant His,C-terminus) (Met1-Arg191) - LS-G141223

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse HAVCR2 comprises 181 amino acids and has a predicted molecular mass of 20.3 kDa. The apparent molecular mass of the protein is approximately 37-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

Select

Human HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) - LS-G142262

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Molecular Weight:

45 kDa

Price:

20 µg/$1,107

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Human HAVCR2 / TIM-3 Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142261

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

23 kDa

Price:

20 µg/$1,107

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