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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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HAO1
hydroxyacid oxidase (glycolate oxidase) 1
HAO1 is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
| Gene Name: | hydroxyacid oxidase (glycolate oxidase) 1 |
| Synonyms: | HAO1, Glycolate oxidase, GOX, GOX1, HAOX1, Hydroxyacid oxidase 1 |
| Target Sequences: | NM_017545 NP_060015.1 Q9UJM8 |
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