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HAMP / Hepcidin

hepcidin antimicrobial peptide

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).

Gene Name: hepcidin antimicrobial peptide
Synonyms: HAMP, Hepcidin antimicrobial peptide, LEAP-1, LEAP1, HEPC, Hepcidin, HFE2B, PLTR, Putative liver tumor regressor
Target Sequences: NM_021175 NP_066998.1 P81172

Publications (6)

1
Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss. Hao-Han Guo , Lei Xiong , Jin-Xiu Pan, Daehoon Lee, Kevin Liu, Xiao Ren, Bo Wang, Xiao Yang, Shun Cui, Lin Mei, Wen-Cheng Xiong. Bone research. 2021 June;9:31. [Full Text Article] [PubMed:34108442] [PMC:PMC8190093]
2
Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure. Igor Spivak, Jyoti Arora, Caitlyn Meinzer, Valerie Durkalski-Mauldin, William M Lee, Christian Trautwein, Robert J Fontana, Pavel Strnad, Acute Liver Failure Study Group (ALFSG). Hepatology (Baltimore, Md.). 2019 May;69:2136-2149. [Full Text Article] [PubMed:30582749]
3
Development of a model for anemia of inflammation that is relevant to critical care. Margit Boshuizen, Robin van Bruggen, Sebastian A Zaat, Marcus J Schultz, Eli Aguilera, Ana Motos, Tarek Senussi, Francesco Antonio Idone, Paolo Pelosi, Antonio Torres, Gianluigi Li Bassi, Nicole P Juffermans. Intensive care medicine experimental. 2019 July;7:47. [Full Text Article] [PubMed:31346819] [PMC:PMC6658638]
4
Iron Protein Succinylate in the Management of Iron Deficiency Anemia: A Comparative Study with Ferrous Sulphate at Low and High Therapeutic Doses. Katia Urso, Javier Leal Martínez-Bujanda, Jaime Moscoso Del Prado. Nutrients. 2021 Mar;13:968. [Full Text Article] [PubMed:33802720] [PMC:PMC8002401]
5
Tolerable upper intake level of iron damages the liver of weaned piglets. Haoxuan Ding, Yang Zhao, Xiaonan Yu, Lingjun Chen, Jianan Han, Jie Feng. Journal of animal physiology and animal nutrition. 2021 July;105:668-677. [Full Text Article] [PubMed:33683742] Related Antibodies: LS-C294486.
6
Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm. Paul Loick , Goran Hamid Mohammad , Ismail Cassimjee, Anirudh Chandrashekar, Pierfrancesco Lapolla, Alison Carrington, Mayra Vera-Aviles, Ashok Handa, Regent Lee , Samira Lakhal-Littleton. Arteriosclerosis, thrombosis, and vascular biology. 2023 May;43:713-725. [Full Text Article] [PubMed:36951059] [PMC:PMC10125116]
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ELISA Kits (34)
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Sandwich (25)
Sandwich CLIA (4)
HAMP / Hepcidin (34)
Human (10)
Mouse (8)
Rat (6)
Bovine (1)
Dog (2)
Guinea pig (1)
Monkey (2)
Pig (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (3)
96-Well Strip Plate (28)
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Yes (4)
Cell Culture Supernatants (7)
Cell Lysates (4)
Cell Supernatant (1)
Plasma (31)
Serum (31)
Tissue Homogenates (10)
Urine (1)
HAMP / Hepcidin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
160 - 100000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Microplate
Rat
78.1 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
HAMP / Hepcidin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
HAMP / Hepcidin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Monkey
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$805
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$816
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$495
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$760
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HAMP / Hepcidin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
HAMP / Hepcidin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
246.9 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$790
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$865
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
HAMP / Hepcidin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
HAMP / Hepcidin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HAMP / Hepcidin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
HAMP / Hepcidin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HAMP / Hepcidin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).