Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
HAMP / Hepcidin
hepcidin antimicrobial peptide
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).
Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss. Hao-Han Guo , Lei Xiong , Jin-Xiu Pan, Daehoon Lee, Kevin Liu, Xiao Ren, Bo Wang, Xiao Yang, Shun Cui, Lin Mei, Wen-Cheng Xiong. Bone research. 2021 June;9:31. [Full Text Article]
[PubMed:34108442]
[PMC:PMC8190093]
2
Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure. Igor Spivak, Jyoti Arora, Caitlyn Meinzer, Valerie Durkalski-Mauldin, William M Lee, Christian Trautwein, Robert J Fontana, Pavel Strnad, Acute Liver Failure Study Group (ALFSG). Hepatology (Baltimore, Md.). 2019 May;69:2136-2149. [Full Text Article]
[PubMed:30582749]
3
Development of a model for anemia of inflammation that is relevant to critical care. Margit Boshuizen, Robin van Bruggen, Sebastian A Zaat, Marcus J Schultz, Eli Aguilera, Ana Motos, Tarek Senussi, Francesco Antonio Idone, Paolo Pelosi, Antonio Torres, Gianluigi Li Bassi, Nicole P Juffermans. Intensive care medicine experimental. 2019 July;7:47. [Full Text Article]
[PubMed:31346819]
[PMC:PMC6658638]
4
Iron Protein Succinylate in the Management of Iron Deficiency Anemia: A Comparative Study with Ferrous Sulphate at Low and High Therapeutic Doses. Katia Urso, Javier Leal Martínez-Bujanda, Jaime Moscoso Del Prado. Nutrients. 2021 Mar;13:968. [Full Text Article]
[PubMed:33802720]
[PMC:PMC8002401]
5
Tolerable upper intake level of iron damages the liver of weaned piglets. Haoxuan Ding, Yang Zhao, Xiaonan Yu, Lingjun Chen, Jianan Han, Jie Feng. Journal of animal physiology and animal nutrition. 2021 July;105:668-677. [Full Text Article]
[PubMed:33683742]
Related Antibodies: LS-C294486.
6
Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm. Paul Loick , Goran Hamid Mohammad , Ismail Cassimjee, Anirudh Chandrashekar, Pierfrancesco Lapolla, Alison Carrington, Mayra Vera-Aviles, Ashok Handa, Regent Lee , Samira Lakhal-Littleton. Arteriosclerosis, thrombosis, and vascular biology. 2023 May;43:713-725. [Full Text Article]
[PubMed:36951059]
[PMC:PMC10125116]
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).