GZMA / Granzyme A

granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

GZMA / Granzyme A (10)

Publications

No (10)

Tag

10His, C-terminus (1)

6His-B2M, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Source

293E Cells (1)

293T Cells (1)

E. coli (2)

Eukaryotic cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (1)

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Mouse GZMA / Granzyme A Protein (Recombinant His) (aa29-260) - LS-G12459

Source:

E. coli

Tag:

His

Molecular Weight:

27.2 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human GZMA / Granzyme A Protein (Recombinant 10His, C-terminus) - LS-G137846

Source:

293E Cells

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

This 252 amino acid recombinant protein has a predicted molecular mass of approximately 28 kD. The protein migrates at about 35 kD in DTT-reducing conditions and about 55 kD in non-reducing conditions by SDS-PAGE.The predicted N-terminal amino acid is Cys

Price:

10 µg/$352; 25 µg/$493

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Human GZMA / Granzyme A Protein (Recombinant His) (aa29-262) - LS-G12457

Source:

Yeast

Tag:

His

Molecular Weight:

27.2 kDa

Price:

10 µg/$307; 50 µg/$482; 100 µg/$722

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Human GZMA / Granzyme A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65785

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.8 kDa

Price:

20 µg/$1,107

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Human GZMA / Granzyme A Protein (Recombinant GST, N-terminus) (aa41-141) - LS-G58806

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GZMA / Granzyme A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76280

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.8 kDa

Price:

20 µg/$150

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GZMA / Granzyme A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115503

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.8 kDa

Price:

100 µg/$494

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Human GZMA / Granzyme A Protein (Recombinant GST) (Full Length) - LS-G28776

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.4 kDa

Price:

2 µg/$439

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Mouse GZMA / Granzyme A Protein (Recombinant 6His-B2M, N-terminus) (aa29-260) - LS-G56313

Source:

E. coli

Tag:

6His-B2M, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human GZMA / Granzyme A Protein (Recombinant His, N-Terminal) (Ile29-Val262) - LS-G132913

Source:

Eukaryotic cells

Tag:

His, N-Terminal

Molecular Weight:

28kDa

Price:

10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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