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Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Gene Name: | GUF1 GTPase homolog (S. cerevisiae) |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | GUF1, Elongation factor 4 homolog, EF-4, GTPase GUF1, GTPase of unknown function 1, Ribosomal back-translocase |
Target Sequences: | NM_021927 NP_068746.2 Q8N442 |
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