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GUCY1B3
guanylate cyclase 1, soluble, beta 3
GUCY1B3 encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
| Gene Name: | guanylate cyclase 1, soluble, beta 3 |
| Family/Subfamily: | Guanyl cyclase , not assigned-Guanyl cyclase |
| Synonyms: | GUCY1B3, GC-S-beta-1, GC-SB3, GCS-beta-1, GUC1B3, GUCB3, GUCSB3, GUCY1B1, GCS-beta-3 |
| Target Sequences: | NM_000857 NP_000848.1 Q02153 |
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