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Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Gene Name: | guanylate cyclase activator 2B (uroguanylin) |
Synonyms: | GUCA2B, Guanylate cyclase activator 2B, UGN, Uroguanylin, GCAP-II |
Target Sequences: | NM_007102 NP_009033.1 Q16661 |
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