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GRWD1 encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase.
Gene Name: | glutamate-rich WD repeat containing 1 |
Synonyms: | GRWD1, CDW4, GRWD, KIAA1942, WD repeat domain 28, WDR28, RRB1 |
Target Sequences: | NM_031485 |
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