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Growth Hormone Receptor / GHR

growth hormone receptor

Growth Hormone Receptor / GHR is a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Name: growth hormone receptor
Synonyms: GHR, Growth hormone receptor, GH receptor, Growth hormone binding protein, Serum binding protein, GHBP
Target Sequences: NM_000163 NP_000154.1 P10912

Publications (1)

1
Growth hormone is permissive for neoplastic colon growth. Chesnokova V, Zonis S, Zhou C, Recouvreux MV, Ben-Shlomo A, Araki T, Barrett R, Workman M, Wawrowsky K, Ljubimov VA, Uhart M, Melmed S. Proceedings of the National Academy of Sciences of the United States of America. 2016 113:E3250-9. (WB; Human) [Full Text Article] [PubMed:27226307] [PMC:PMC4988562]

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Antibodies (54)
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Growth Hormone Receptor / GHR (92)
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Growth Hormone Receptor / GHR ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.137 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Growth Hormone Receptor / GHR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$798
Growth Hormone Receptor / GHR ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
Growth Hormone Receptor / GHR Antibody - Immunohistochemistry image of paraffin-embedded human liver tissue at a dilution of 1:100
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Growth Hormone Receptor / GHR Antibody - Western Blot analysis of extracts from SKOV3 cells using GHR Antibody.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Growth Hormone Receptor / GHR Antibody - Detection limit for recombinant GST tagged GHR is approximately 0.1 ng/ml as a capture antibody.
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Growth Hormone Receptor / GHR Mouse anti-Human Monoclonal (3A12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Growth Hormone Receptor / GHR Antibody - Western blot analysis GHR using HepG2 whole cells lysates
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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Growth Hormone Receptor / GHR Rabbit anti-Mouse Monoclonal (Preservative Free) (014) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
Growth Hormone Receptor / GHR Antibody - GHR / Growth Hormone Receptor antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
Growth Hormone Receptor / GHR Antibody - Western blot of Human OVCAR-3. GHR antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa218-267) Antibody
Human
WB
Unconjugated
100 µl/$424
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Growth Hormone Receptor / GHR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$412
Growth Hormone Receptor / GHR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
71.5 kDa
20 µg/$215
Growth Hormone Receptor / GHR ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Select
Growth Hormone Receptor / GHR Rabbit anti-Mouse Polyclonal Antibody
Mouse
IHC, IHC-P
Unconjugated
20 µl/$286; 100 µl/$435
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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Growth Hormone Receptor / GHR Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
Growth Hormone Receptor / GHR Antibody - Western blot of recombinant Growth Hormone Receptor / GHR.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa315-574) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
Growth Hormone Receptor / GHR Antibody - Western blot of recombinant Growth Hormone Receptor / GHR.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa315-574) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279
Growth Hormone Receptor / GHR Antibody - Western blot of recombinant Growth Hormone Receptor / GHR.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa315-574) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
Growth Hormone Receptor / GHR Antibody - Western blot of recombinant Growth Hormone Receptor / GHR.
Select
Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (aa315-574) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
Growth Hormone Receptor / GHR Antibody - Western blot - Anti-GHR/Growth Hormone R Antibody
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Growth Hormone Receptor / GHR Rabbit anti-Mouse Polyclonal (aa231-247) Antibody
Mouse, Rat
WB
Unconjugated
10 µg/$318; 100 µg/$470
Growth Hormone Receptor / GHR Antibody - Western blot of recombinant Growth Hormone Receptor / GHR.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Growth Hormone Receptor / GHR Rabbit anti-Mouse Polyclonal (aa36-266) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
ELISA
Unconjugated
100 µl/$450
Growth Hormone Receptor / GHR Antibody - Western blot of GHR Antibody with human Uterus Tumor lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Growth Hormone Receptor / GHR Antibody - Western blot analysis of extracts of various cell lines, using GHR antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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Growth Hormone Receptor / GHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25 of 92 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).