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GRM7 / MGLUR7

glutamate receptor, metabotropic 7

L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: glutamate receptor, metabotropic 7
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM7, GLUR7, MGLU7, MGLUR7, GPRC1G
Target Sequences: NM_000844 NP_000835.1 Q14831

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Products
Antibodies (37)
Primary (37)
GRM7 / MGLUR7 (37)
Human (37)
Mouse (17)
Rat (23)
Bovine (9)
Chicken (4)
Chimpanzee (3)
Dog (9)
Gibbon (3)
Guinea pig (3)
Horse (7)
Monkey (7)
Orangutan (3)
Pig (1)
Primate (1)
Rabbit (7)
Xenopus (3)
Zebrafish (1)
IHC (10)
IHC-P (6)
WB (33)
Flo (3)
ELISA (13)
ICC (3)
IF (6)
Peptide-ELISA (5)
rabbit (32)
mouse (4)
goat (1)
Product Group
GPCR Database Antibodies (4)
IHCPlus (3)
PathPlus Neuro (1)
IgG (19)
IgG1 (2)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (33)
1H5 (1)
7G8A2 (1)
7G8D3 (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (24)
aa240-269 (7)
C-Terminus (6)
N-Terminus (3)
320-400 aa, Internal (1)
840-920 aa, C-terminal (1)
Extracellular Domain (1)
aa340-389 (1)
aa351-400 (1)
aa373-386 (1)
aa866-915 (1)
pSer862 (1)
No (37)
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bovine, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$440
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 7 ug/ml.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$440
GRM7 / MGLUR7 Antibody - Immunofluorescence analysis of A549 cells, using GRM7 Antibody. The picture on the right is blocked with the synthesized peptide.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa351-400) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GRM7 / MGLUR7 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human brain, cortex, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GRM7 / MGLUR7 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR7 Antibody. The picture on the right is blocked with the synthesized peptide.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa866-915) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GRM7 / MGLUR7 Antibody - Immunofluorescent analysis of mGLUR7 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with Alexa Fluor 647-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (320-400 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GRM7 / MGLUR7 Antibody - Immunofluorescence analysis of SMMC-7721 cells using GRM7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
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GRM7 / MGLUR7 Mouse anti-Human Monoclonal (7G8D3) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
GRM7 / MGLUR7 Antibody - Detection limit for recombinant GST tagged GRM7 is approximately 0.03 ng/ml as a capture antibody.
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GRM7 / MGLUR7 Mouse anti-Human Monoclonal (1H5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Rat, Human
WB
Biotin Conjugated
100 µl/$1,154
GRM7 / MGLUR7 Antibody - Western blot of mGluR-7 antibody
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (840-920 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GRM7 / MGLUR7 Antibody - GRM7 / MGLUR7 antibody Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Horse, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4-6 ug/ml.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
GRM7 / MGLUR7 Antibody - Western blot analysis using GRM7 mAb against HEK293 (1) and GRM7 (AA: 454-590)-hIgGFc transfected HEK293 (2) cell lysate.
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GRM7 / MGLUR7 Mouse anti-Human Monoclonal (7G8A2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
GRM7 / MGLUR7 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using GRM7 antibody.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
GRM7 / MGLUR7 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
GRM7 / MGLUR7 Antibody - Western blot of HUVEC cell lysate using mGluR7 Antibody
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa240-269) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa240-269) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa240-269) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa240-269) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa240-269) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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GRM7 / MGLUR7 Mouse anti-Human Monoclonal (C-Terminus) Antibody
Human
Flo
Unconjugated
100 µg/$884
GRM7 / MGLUR7 Antibody - Western blot analysis of the lysates from HUVECcells using GRM7 antibody.
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GRM7 / MGLUR7 Rabbit anti-Human Polyclonal (aa340-389) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 37 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).