GRM5 / MGLUR5

glutamate receptor, metabotropic 5

Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia. Summary of expresson: GRM5 has been reported to be expressed in various regions of the brain as well as in the spinal cord and dorsal root ganglia.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

GRM5 / MGLUR5 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human GRM5 / MGLUR5 Protein (Recombinant GST, N-terminus) (aa419-518) - LS-G58762

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GRM5 / MGLUR5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77333

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

132.47 kDa

Price:

20 µg/$215

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GRM5 / MGLUR5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126209

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

132.47 kDa

Price:

100 µg/$710

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