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GRIN2C / NMDAR2C / NR2C

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

GRIN2C / NMDAR2C / NR2C is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Family/Subfamily: Ion Channel , Glutamate receptor - ionotropic (NMDA receptor)
Synonyms: GRIN2C, GluN2C, NMDA receptor 2C, NMDAR2C, NR2C, GluR epsilon 3
Target Sequences: NM_000835 NP_000826.2 Q14957

Publications (2)

1
Salicylate enables cochlear arachidonic-acid-sensitive NMDA receptor responses. Ruel J, Chabbert C, Nouvian R, Bendris R, Eybalin M, Leger CL, Bourien J, Mersel M, Puel JL. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 28:7313-23. [PubMed:18632935]
2
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM. eLife. 2014 3:e02200. (WB; Human) [PubMed:24867637] [PMC:PMC4033189] Related Antibodies: LS-C157785.

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Products
Antibodies (38)
Primary (38)
GRIN2C / NMDAR2C / NR2C (38)
Human (33)
Mouse (17)
Rat (10)
Bovine (2)
Dog (2)
Primate (2)
Rabbit (3)
IHC (12)
IHC-P (6)
WB (29)
ELISA (12)
IF (1)
IP (2)
Peptide-ELISA (3)
rabbit (37)
mouse (1)
Product Group
IHCPlus (2)
IgG (25)
polyclonal pc (38)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (22)
aa567-595 (7)
aa69-118 (4)
Internal (2)
N-Terminus (1)
Pro986 (1)
aa25-130 (1)
aa43-242 (1)
aa937-986 (1)
pSer1096 (1)
pSer1244 (1)
No (37)
Yes (1)
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa69-118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa69-118) (HRP) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa69-118) (Biotin) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
GRIN2C / NMDAR2C / NR2C Antibody - Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa69-118) (FITC) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
GRIN2C / NMDAR2C / NR2C Antibody - GRIN2C Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The GRIN2C antibody detected the GRIN2C protein (arrow).
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa567-595) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using GRIN2C Antibody at dilution of 1:100
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
GRIN2C / NMDAR2C / NR2C Antibody - Western blot of rat cerebellar lysate showing specific immunolabeling of the ~140k NR2C subunit of the NMDA Receptor.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
10 µg/$469
GRIN2C / NMDAR2C / NR2C Antibody - Western blot analysis of NMDAR2C expression in SKOVCAR (A); HEK293T (B); SP2/0 (C) whole cell lysates.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
GRIN2C / NMDAR2C / NR2C Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
GRIN2C / NMDAR2C / NR2C Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using GRIN2C Polyclonal Antibody at dilution of 1:100.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GRIN2C / NMDAR2C / NR2C Antibody - Immunohistochemistry analysis of NMDAε3 antibody in paraffin-embedded human brain tissue.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa937-986) Antibody
Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
GRIN2C / NMDAR2C / NR2C Antibody - IHC of NMDA3 (P986) pAb in paraffin-embedded human brain tissue.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (Pro986) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal (aa567-595) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
200 µl/$734
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Mouse Polyclonal (aa567-595) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Mouse Polyclonal (aa567-595) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Mouse Polyclonal (aa567-595) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Mouse Polyclonal (aa567-595) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Mouse Polyclonal (aa567-595) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
GRIN2C / NMDAR2C / NR2C Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$431
GRIN2C / NMDAR2C / NR2C Antibody - This antibody recognizes the 180 kDa 2A and 2B subunits, however, this blot was done done on the cerebellum of an older animal where there is not much 2A and 2B present. In a younger animal, you will see the 180 kDa band clearly.
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GRIN2C / NMDAR2C / NR2C Rabbit anti-Rat Polyclonal (aa25-130) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
10 µl/$386
Viewing 1-25 of 38 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).