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GRIN2A / NMDAR2A / NR2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

GRIN2A / NMDAR2A / NR2A is a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Family/Subfamily: Ion Channel , Glutamate receptor - ionotropic (NMDA receptor)
Synonyms: GRIN2A, EPND, HNR2A, GluN2A, GluR epsilon 1, NMDA receptor 2A, NMDAR2A, NR2A, NMDA receptor subtype 2A
Target Sequences: NM_000833 NP_000824.1 Q12879

Publications (1)

1
Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer's Disease. Jack Hashem, Mei Hu, Jian Zhang, Fei Gao, Chu Chen. Molecular neurobiology. 2021 Aug;;58:4122-4133. [Full Text Article] [PubMed:33939165] [PMC:PMC8282737 (ava] Related Antibodies: LS-B7707.

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ELISA Kits (8)
Competitive EIA (1)
Development Kit (1)
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GRIN2A / NMDAR2A / NR2A (8)
Human (6)
Mouse (1)
Rat (1)
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DevKit DuoPlus (1)
96-Well Microplate (3)
96-Well Strip Plate (4)
Antibody Pair and Standard (1)
No (8)
Cell Culture Supernatants (1)
Cell Lysates (5)
Plasma (3)
Serum (3)
Tissue Homogenates (6)
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Development Kit
Antibody Pair and Standard
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Competitive EIA
96-Well Microplate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$909
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich CLIA
96-Well Microplate
Human
6.86 - 5000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$792
GRIN2A / NMDAR2A / NR2A ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).