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GRIN2A / NMDAR2A / NR2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2A / NMDAR2A / NR2A is a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
| Gene Name: | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| Family/Subfamily: | Ion Channel , Glutamate receptor - ionotropic (NMDA receptor) |
| Synonyms: | GRIN2A, EPND, HNR2A, GluN2A, GluR epsilon 1, NMDA receptor 2A, NMDAR2A, NR2A, NMDA receptor subtype 2A |
| Target Sequences: | NM_000833 NP_000824.1 Q12879 |
Publications (1)
1
Inhibition of 2-Arachidonoylglycerol Metabolism Alleviates Neuropathology and Improves Cognitive Function in a Tau Mouse Model of Alzheimer's Disease. Jack Hashem, Mei Hu, Jian Zhang, Fei Gao, Chu Chen. Molecular neurobiology. 2021 Aug;;58:4122-4133. [Full Text Article]
[PubMed:33939165]
[PMC:PMC8282737 (ava]
Related Antibodies: LS-B7707.
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GRIN2A / NMDAR2A / NR2A
(93)
Reactivity
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(74)
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(49)
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(50)
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(10)
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(9)
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(25)
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(58)
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(5)
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6His, N-terminus
(2)
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E. coli
(2)
GRIN2A / NMDAR2A / NR2A Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$485
GRIN2A / NMDAR2A / NR2A Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat
IHC, IHC-P, WB
Unconjugated
50 µl/$460
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
GRIN2A / NMDAR2A / NR2A Mouse anti-Rat Monoclonal (aa75-325) (S327-95) Antibody
Mouse, Rat, Human
ICC, IHC, WB
Unconjugated
100 µg/$442
E. coli
6His, N-terminus
62.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1050-1100) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1115-1164) Antibody
Rat, Human
WB
Unconjugated
100 µl/$424
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa31-555) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1291-1318) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
GRIN2A / NMDAR2A / NR2A Mouse anti-Human Monoclonal (3G10F9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
E. coli
6His, N-terminus
31.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P
Unconjugated
60 µl/$460
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1411-1427) Antibody
Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µg/$431
GRIN2A / NMDAR2A / NR2A Mouse anti-Human Monoclonal (APC) Antibody
Rat, Human
ICC, IHC, WB
APC Conjugated
100 µl/$1,119
GRIN2A / NMDAR2A / NR2A Rabbit anti-Human Polyclonal (aa1057-1084) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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