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GRIN1 / NMDAR1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity.

Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 1
Family/Subfamily: Ion Channel , Glutamate receptor - ionotropic (NMDA receptor)
Synonyms: GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1, N-methyl-D aspartate receptor
Target Sequences: NM_007327 NP_015566.1 Q05586

Publications (2)

1
REST-Governed Gene Expression Profiling in a Neuronal Cell Model Reveals Novel Direct and Indirect Processes of Repression and Up-Regulation. Garcia-Manteiga JM, Bonfiglio S, Folladori L, Malosio ML, Lazarevic D, Stupka E, Cittaro D, Meldolesi J. Frontiers in cellular neuroscience. 2015 9:438. (WB; Human) [Full Text Article] [PubMed:26617488] [PMC:PMC4639699] Related Antibodies: LS-B7013.
2
Direct binding of Toll-like receptor 4 to ionotropic glutamate receptor N-methyl-D-aspartate subunit 1 induced by lipopolysaccharide in microglial cells N9 and EOC 20. Cui J, Yu S, Li Y, Li P, Liu F. International journal of molecular medicine. 2018 March;41:1323-1330. (Human) [Full Text Article] [PubMed:29286078] [PMC:PMC5819937] Related Antibodies: LS-B13901.

☰ Filters
Products
ELISA Kits (12)
Cell-Based (1)
Cell-Based Phosphorylation (2)
Custom (3)
Sandwich (6)
GRIN1 / NMDAR1 (12)
Human (6)
Mouse (5)
Rat (6)
Dog (1)
96-Well Microplate (4)
96-Well Strip Plate (8)
No (12)
Adherent Cell Cultures (3)
Cell Lysates (2)
Plasma (4)
Serum (4)
Tissue Homogenates (4)
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
GRIN1 / NMDAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
GRIN1 / NMDAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
GRIN1 / NMDAR1 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
GRIN1 / NMDAR1 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
GRIN1 / NMDAR1 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
GRIN1 / NMDAR1 ELISA Kit
Select
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
GRIN1 / NMDAR1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).