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GRIK1 / GLUR5
glutamate receptor, ionotropic, kainate 1
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
| Gene Name: | glutamate receptor, ionotropic, kainate 1 |
| Family/Subfamily: | Ion Channel , Glutamate receptor - ionotropic (NMDA receptor) |
| Synonyms: | GRIK1, GluR-5, GLUR5, EEA3, GluK1, Glutamate receptor 5, EAA3, GLR5 |
| Target Sequences: | NM_000830 NP_000821.1 P39086 |
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