GRIA2 / GLUR2

glutamate receptor, ionotropic, AMPA 2

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

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Products

ELISA Kits (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Sandwich (5)

Target

GRIA2 / GLUR2 (7)

Reactivity

Human (4)

Mouse (4)

Rat (3)

Format

96-Well Microplate (2)

96-Well Strip Plate (5)

Publications

No (7)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

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Human GRIA2 / GLUR2 (Sandwich ELISA) ELISA Kit - LS-F8851

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

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Mouse/Human/Rat Phospho-GRIA2 / GLUR2 (Ser880) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1519

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat GRIA2 / GLUR2 (Cell-Based ELISA) ELISA Kit - LS-F2018

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Rat GRIA2 / GLUR2 (Sandwich ELISA) ELISA Kit - LS-F66624

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse GRIA2 / GLUR2 (Sandwich ELISA) ELISA Kit - LS-F66662

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human GRIA2 / GLUR2 (Sandwich ELISA) ELISA Kit - LS-F66989

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Mouse GRIA2 / GLUR2 (Sandwich ELISA) ELISA Kit - LS-F8852

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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