GPX4 / MCSP

glutathione peroxidase 4

GPX4 / MCSP is a member of the glutathione peroxidase protein family. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. The encoded protein has been identified as a moonlighting protein based on its ability to serve dual functions as a peroxidase as well as a structural protein in mature spermatozoa. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. Alternative splicing results in multiple transcript variants.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

GPX4 / MCSP (5)

Publications

No (5)

Tag

6His-SUMO, N-terminus (1)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Mouse (1)

Orangutan (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Purification

Purified (1)

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Mouse GPX4 / MCSP Protein (Recombinant His-T7) (aa74-197) - LS-G15112

Source:

E. coli

Tag:

His-T7

Molecular Weight:

18.1 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human GPX4 / MCSP Protein (Recombinant His-GST) (aa74-197) - LS-G15110

Source:

E. coli

Tag:

His-GST

Molecular Weight:

46.2 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Human GPX4 / MCSP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78032

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.1 kDa

Price:

20 µg/$150

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Orangutan GPX4 / MCSP Protein (Recombinant 6His-SUMO, N-terminus) (aa1-170) - LS-G56748

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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GPX4 / MCSP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118207

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.1 kDa

Price:

100 µg/$494

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